Study of Reality-monitoring Process and Influence of Stress Using an Electrophysiological Approach

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Reality-monitoring is a crucial cognitive process in daily life to remember the source of an information. Deficits of reality-monitoring have been shown into the continuum of schizophrenia, suggesting a preexisting alteration in population at-risk for psychosis that will be exacerbated during psychotic transition. It is admitted that stress plays a crucial role in the psychotic transition and can alter cognitive performances. However, less is known about the effects of stress on reality-monitoring, even though this process appears to be central in psychotic disorders. The aim of this project is to investigate the effect of stress on reality-monitoring, both on behavioral and neurophysiological aspects

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 30
Healthy Volunteers: t
View:

• Right-handed Men and Women aged between 18 and 30

• Having given their written informed consent

• For women: oral contraceptive use

• French speakers and readers

Locations
Other Locations
France
Centre Hospitalier le Vinatier
RECRUITING
Bron
Contact Information
Primary
SARTLET Lydie
lydie.sartelet@ch-le-vinatier.fr
0437915531
Backup
Mondino Marine, PhD
marine.mondino@ch-le-vinatier.fr
0437915565
Time Frame
Start Date: 2024-04-25
Estimated Completion Date: 2025-11-16
Participants
Target number of participants: 40
Treatments
Experimental: active stress group
20 healthy subjects will be subject to the active condition of a standardized stress protocol
Placebo_comparator: placebo stress group
20 healthy subjects will be subject to the placebo condition of a standardized stress protocol.
Related Therapeutic Areas
Sponsors
Leads: Hôpital le Vinatier

This content was sourced from clinicaltrials.gov