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Sensory and Cognitive Predictions, and Their Disruptions in Schizophrenia

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Disturbances in the sense of self and time could play an important role in the development of psychotic symptoms. Previous work has shown that patients have difficulty preparing to process information on the scale of a second, but are abnormally disturbed by slightly asynchronous information on the millisecond scale. In both cases, the anomalies could explain the patients' unusual experience of time. The hypothesis in neurotypical patients is that small delays or asynchronies asynchronies are treated as irrelevant information and ignored and ignored, whereas in patients suffering from schizophrenia they would disrupt the flow of time. This hypothesis is tested with a new visual illusion.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:

• Male or female;

• Age between 18 and 60 inclusive;

• Subject having dated and signed the consent form prior to the start of any trial-related procedure (guardian or curator where applicable);

• Member of a social security scheme or beneficiary of such a scheme.

Locations
Other Locations
France
CHU Sainte Marguerite, APHM
RECRUITING
Marseille
Centre Hospitalier Drôme Vivarais
RECRUITING
Montéléger
Contact Information
Primary
Anne Giersch, MD PhD
giersch@unistra.fr
0033 3 88 116471
Backup
Naoual MELLOUKI BENDIMRED, PhD
unic@cpn-laxou.com
0383925267
Time Frame
Start Date: 2024-06-28
Estimated Completion Date: 2027-10-28
Participants
Target number of participants: 68
Treatments
Experimental: effect of trajectory perturbation
All participants will run the task consisting in 2 squares moving towards each other. On each trial they will answer whether the squares touch or do not touch. All participants are tested with all experimental conditions. The rate of 'touch' responses will be compared when there is a trajectory perturbation without rebound vs. a trajectory with perturbation with rebound vs. a trajectory without perturbation and without rebound vs. a trajectory without perturbation and with rebound.
Related Therapeutic Areas
Sponsors
Collaborators: Institut National de la Santé Et de la Recherche Médicale, France
Leads: Centre Psychothérapique de Nancy

This content was sourced from clinicaltrials.gov