Effect of Olfactory Training on Olfactory Dysfunction Patients in Hong Kong Population

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Olfactory dysfunction \> 6 months and \< 5 years

Locations
Other Locations
Hong Kong Special Administrative Region
Pamela Youde Nethersole Eastern Hospital
RECRUITING
Hong Kong
Contact Information
Primary
Kai Chuen Fergus Wong, FRCSEd(ORL)
wkc568@ha.org.hk
64600771
Backup
Ka Chung Kwan, FRCSEd(ORL)
64600056
Time Frame
Start Date: 2022-07-01
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 80
Treatments
Experimental: Treatment arm
Olfactory training by neurological chemosensory stimulation using aromatic substances delivered via diffusers. Four aromatic substances will be used. Each substance will be given for 20 seconds sequentially, providing a total of 80 seconds of olfactory stimulation three times per day for 3 months.
Placebo_comparator: Control arm
Same diffuser will be given to control group. All of the four essential oils will be replaced by normal saline using the same packing. Same treatment regime of 20 seconds for each diffuser three times per day for 3 months will be instructed to control group patients.
Related Therapeutic Areas
Sponsors
Leads: Pamela Youde Nethersole Eastern Hospital

This content was sourced from clinicaltrials.gov