Learn About Spasmus Nutans

What is the definition of Spasmus Nutans?

Spasmus nutans is a disorder affecting infants and young children. It involves rapid, uncontrolled eye movements, head bobbing, and sometimes, holding the neck in an abnormal position.

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What are the causes of Spasmus Nutans?

Most cases of spasmus nutans begin between age 4 months and 1 year. It usually goes away by itself in several months or years.

The cause is unknown, although it may be associated with other medical conditions. A link with iron or vitamin D deficiency has been suggested. In very rare cases, symptoms similar to spasmus nutans may be due to certain types of brain tumors or other serious conditions.

What are the symptoms of Spasmus Nutans?

Symptoms of spasmus nutans include:

  • Small, quick, side-to-side eye movements called nystagmus (both eyes are involved, but each eye may move differently)
  • Head nodding
  • Head tilting
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What are the current treatments for Spasmus Nutans?

Spasmus nutans that isn't related to another medical problem, such as brain tumor, requires no treatment. If the symptoms are caused by another condition, the provider will recommend appropriate treatment.

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What is the outlook (prognosis) for Spasmus Nutans?

Usually, this disorder goes away on its own without treatment.

When should I contact a medical professional for Spasmus Nutans?

Call for an appointment with your child's provider if your child has rapid, movements of the eyes, or head nodding. The provider will need to perform an exam to rule out other possible causes for the symptoms.

What are the latest Spasmus Nutans Clinical Trials?
A Phase I Open-Label Pilot Study to Investigate the Feasibility, Safety, Tolerability and Efficacy of Daily Administration of Tricaprilin in Subjects With Infantile Spasms

Summary: The purpose of this study is to assess the safety, tolerability, and efficacy of tricaprilin in subjects with infantile spasms. This is a single-arm, open-label, pilot study in up to 10 subjects with infantile spasms.

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A Phase 3, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of AMZ002, Compared to Vigabatrin, in the Treatment of Infantile Spasms

Summary: The main purpose of this study is to evaluate the efficacy of AMZ002 compared to Vigabatrin in participants with newly diagnosed infantile spasms (IS).

What are the Latest Advances for Spasmus Nutans?
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Efficacy of pulse intravenous methylprednisolone in epileptic encephalopathy: a randomised controlled trial.
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Current and promising therapeutic options for Dravet syndrome.
Who are the sources who wrote this article ?

Published Date: May 04, 2021
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Hertle RW, Hanna NN. Supranuclear eye movement disorders, acquired and neurologic nystagmus. In: Lambert SR, Lyons CJ, eds. Taylor and Hoyt's Pediatric Ophthalmology and Strabismus. 5th ed. Philadelphia, PA: Elsevier; 2017:chap 90.

Rucker JC, Lavin PJM. Neuro-ophthalmology: ocular motor system. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley's and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 18.