A Machine Learning Approach to Infantile Spasms Recognition in Video Recordings

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

Infantile spasms are a type of seizure linked to developmental issues. Unfortunately, they are often misdiagnosed, causing delays in treatment. The purpose of this study is to develop a computer program that can reliably differentiate infantile spasms from similar, yet benign movements in videos. This computer program will learn from videos taken by parents of study participants. Quickly recognizing and treating infantile spasms is crucial for ensuring the best developmental outcomes.

Eligibility
Participation Requirements
Sex: All
Maximum Age: 2
Healthy Volunteers: f
View:

• Participant age less than 24 months

• Participant evaluated in the Johns Hopkins Outpatient Center, Johns Hopkins Pediatric Emergency Department or Johns Hopkins Inpatient Units due to spells of abnormal movement or seizure

• Participant evaluated by a pediatric neurologist during the outpatient or inpatient visit at Johns Hopkins Hospital

• At least one video recording of the spell of abnormal movement produced by the parent/guardian available for provider review

Locations
United States
Maryland
Johns Hopkins Hospital
RECRUITING
Baltimore
Contact Information
Primary
Glenn Rivera, MD
griver14@jh.edu
410-955-4259
Time Frame
Start Date: 2024-08-26
Estimated Completion Date: 2026-05
Participants
Target number of participants: 200
Treatments
Confirmed Epileptic Spasms (Positive Class)
Participants diagnosed with infantile spasms based upon historical data and supportive electroencephalography data (i.e. hypsarrhythmia or modified hypsarrhythmia background).
Epileptic Spasm Mimics (Negative Class)
Participants diagnosed with non-epileptic movements (e.g. Sandifer syndrome, shuddering attacks, stretching, stereotypy, startle reflex, writhing movements, jitteriness, sleep myoclonus) based upon historical data and supportive electroencephalography data (when available).
Awake and Alert (Negative Class)
Participants exhibiting spontaneous, subtle movements in the awake and alert state.
Sponsors
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov