IMPACT, a Supervised Rehabilitation Program for Spastic Ataxias: A Rater-blinded, Randomized Controlled Trial

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases. Unfortunately, little effort is made to develop non-pharmacological treatments specific to spastic ataxias despite the detrimental impact of the disease on several aspects of an individual's life and the high cost of falls for society each year. The three objectives of this project are: 1) to determine the effect of a 12-week rehabilitation program on disease severity as compared with usual care for individuals with spastic ataxias; 2) to identify which factors can help (or not) the implementation of the program in the clinical settings (reel world); and 3) to explore the cost-benefits of IMPACT \[rehabIlitation prograM for sPAstiC aTaxias\]. The team has developed the program to specifically target symptoms present in these patients and was previously pilot-tested. Based on the results obtained in this pilot project, positive effects are expected concerning the disease severity of participants. The investigators want, with this project, provide to health care professionals an option to offer better-suited services to people living with spastic ataxia worldwide.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: f
View:

• have a confirmed genetic diagnosis of ARSACS or SPG7

• be able to maintain standing position and to transfert

• be authorized by their treating neurologist

• speak French or English

• be able to give informed consent.

Locations
Other Locations
Canada
CIUSSS de la Capitale-Nationale, Hôpital de Baie-Saint-Paul
NOT_YET_RECRUITING
Baie-saint-paul
CIUSSS de la Capitale-Nationale, Hôpital de La Malbaie
NOT_YET_RECRUITING
La Malbaie
CIUSSS du Centre-Sud-de-l'Île-de-Montréal, installation Centre de réadaptation Lucie-Bruneau
RECRUITING
Montreal
CIUSSS de la Capitale-Nationale, installation IRDPQ
RECRUITING
Québec
Clinique des maladies neuromusculaires du Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Saguenay-Lac-Saint-Jean, installation Hôpital Jonquière
RECRUITING
Saguenay
Contact Information
Primary
Elise Duchesne, Ph D.
educhesn@uqac.ca
418-590-3552
Backup
Andrée Hardy
guichetunique.slsj@ssss.gouv.qc.ca
418 541-1234
Time Frame
Start Date: 2024-02-01
Estimated Completion Date: 2027-03
Participants
Target number of participants: 84
Treatments
No_intervention: Control group
The control group will receive their usual care and will be asked to continue their usual activities and exercises for the whole project duration. Only one clinical guide exists for ataxia interventions and no specific guidelines for physiotherapy and occupational therapy interventions are specified in this guide in terms of frequency, duration and type of interventions that are effective with this population. Patients generally have an annual follow-up with a doctor or a clinical nurse at a Neuromuscular Diseases Clinic. Patients are then referred if needed for follow-up with the physiotherapist and occupational therapist. Typically, patients are referred to physiotherapy for mobility-related needs such as the introduction of a walking aid, orthotic and sometimes teaching an exercise program. In occupational therapy, patients are referred for needs such as the introduction of technical aids, home adaptation or the introduction of a wheelchair.
Experimental: Intervention group
The intervention group will follow a 12-week rehabilitation program, 3 times a week (two sessions in a therapy room and one session of aquatherapy).
Sponsors
Collaborators: Cégep de Jonquière, Muscular Dystrophy Canada, Université du Québec a Montréal, McGill University, Université de Sherbrooke, Corporation de recherche et d'action sur les maladies héréditaires (CORAMH), University of Alberta, University of Calgary, Integrated University Health and Social Services Center of the Capitale-Nationale, Laval University, Centre intégré universitaire de santé et de services sociaux du Saguenay-Lac-St-Jean
Leads: Université du Québec à Chicoutimi

This content was sourced from clinicaltrials.gov