Twice Weekly Outpatient Rehabilitation Intervention for Young Children With Spinal Muscular Atrophy Treated With Genetic Based Therapies: A Feasibility Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

An outpatient rehabilitation program for children (6 months to less than 6 years old) with Spinal Muscular Atrophy (SMA) treated with genetic based therapies is being studied. Participants will participate in a 12-week therapy program where they receive 45 minutes each of occupational therapy and physical therapy each week. Home exercises will also be prescribed to be completed 5 days per week. At the end of the therapy program, there will be a 12-week period of no therapy where only home exercises will be completed. Assessments and program evaluation will occur at the beginning (Week 0) and end of the rehabilitation program (Week 24), then at the end of the no therapy block (week 24).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 6
Healthy Volunteers: f
View:

• SMA (Type I, II or III) diagnosis;

• Receives genetic based therapy;

• Aged 6 months to less than 6 years old;

• Able to participate in weekly therapy at Holland Bloorview (i.e., can attend in-person sessions);

• Able to bring appropriate respiratory equipment to weekly therapy sessions, if required;

• Substitute decision makers (SDMs) must be able to speak and read English;

• Child participant must be able to understand/follow directions in English, as age appropriate;

• SDMs must consent to participate on behalf of their child.

Locations
Other Locations
Canada
Holland Bloorview Kids Rehabilitation Hospital
RECRUITING
Toronto
Contact Information
Primary
Laura McAdam, MD
neuromuscular.research@hollandbloorview.ca
416-425-6220
Time Frame
Start Date: 2022-01-01
Estimated Completion Date: 2024-12
Participants
Target number of participants: 10
Treatments
Experimental: Intervention
Participants will participate in the rehabilitation intervention.
Sponsors
Leads: Holland Bloorview Kids Rehabilitation Hospital

This content was sourced from clinicaltrials.gov