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Neuromodulation for Rehabilitation of Post-Stroke Fatigue: An rTMS Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 34
Maximum Age: 80
Healthy Volunteers: f
View:

• 34 - 80 years of age

• more than 6 months post-stroke

• Clinically present fatigue

Locations
United States
Georgia
Atlanta VA Medical and Rehab Center, Decatur, GA
RECRUITING
Decatur
Contact Information
Primary
John H Kindred
John.Kindred1@va.gov
(970) 426-9350
Backup
Christina Young
christina.young3@va.gov
(404) 432-6111
Time Frame
Start Date: 2023-04-10
Estimated Completion Date: 2027-10-29
Participants
Target number of participants: 60
Treatments
Experimental: Real M1 High Frequency rTMS
Participants will be randomly assigned to receive high-frequency repetitive transcranial magnetic stimulation (rTMS) to the top of their head for approximately 40 minutes.
Sham_comparator: Sham rTMS
Participants will be randomly assigned to receive sham/placebo repetitive transcranial magnetic stimulation (rTMS) to the their head for approximately 40 minutes. This is a control condition.
Related Therapeutic Areas
Sponsors
Leads: VA Office of Research and Development
Collaborators: Joseph Maxwell Cleland VA Medical Center

This content was sourced from clinicaltrials.gov