Latest Advances

  • Condition: Brain Metastasis from Soft Tissue Sarcomas
  • Journal: Anticancer research
  • Treatment Used: Combined Surgery and Radiotherapy
  • Number of Patients: 509
  • Published —
This study tested the safety and efficacy of using a combined surgery and radiotherapy regimen to treat patients with brain metastases that they acquired from their soft tissue sarcoma.
  • Condition: Epithelioid Sarcoma
  • Journal: The Lancet. Oncology
  • Treatment Used: Tazemetostat
  • Number of Patients: 62
  • Published —
This study evaluated the safety and effectiveness of Tazemetostat, an oral selective EZH2 inhibitor, in patients with epithelioid sarcoma.
  • Condition: Korean Patients with Advanced Soft Tissue Sarcoma (STS)
  • Journal: Targeted oncology
  • Treatment Used: Pazopanib
  • Number of Patients: 347
  • Published —
This study evaluated the outcomes of Korean patients with advanced soft tissue sarcoma (rare type of cancer that begins in the tissues that connect, support and surround other body structures; STS) treated with pazopanib.
  • Condition: High-Risk Soft Tissue Sarcomas
  • Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Treatment Used: Add-on Chemotherapy
  • Number of Patients: 287
  • Published —
The study researched the outcomes of chemotherapy in treating high-risk soft tissue sarcomas.
  • Condition: Children and Young Adults with Refractory or Recurrent Solid Tumors
  • Journal: European journal of cancer (Oxford, England : 1990)
  • Treatment Used: Combination of Bevacizumab, Sorafenib, and Low-dose Cyclophosphamide
  • Number of Patients: 24
  • Published —
The purpose of the study was to evaluate the effectiveness of the combination of bevacizumab, sorafenib, and low-dose cyclophosphamide in children and young adults with refractory or recurrent solid tumors.
  • Condition: Synovial Sarcoma
  • Journal: Anticancer research
  • Treatment Used: Chemotherapy
  • Number of Patients: 106
  • Published —
In this study, researchers evaluated the effects of providing chemotherapy prior to surgery for patients with synovial sarcoma.
  • Condition: Metastatic and/or Un-Resectable Sarcomas
  • Journal: European journal of cancer (Oxford, England : 1990)
  • Treatment Used: Lurbinectedin as Single Agent or in Combination with Conventional Chemotherapy
  • Number of Patients: 42
  • Published —
This study determined the disease control rate at 24 weeks of lurbinectedin alone or with chemotherapy in soft tissue sarcoma (STS).
  • Condition: Primary Pleural Synovial Sarcoma
  • Journal: Medicine
  • Treatment Used: apatinib
  • Number of Patients: 1
  • Published —
The purpose of the paper was to report a case of primary pleural synovial sarcoma treated with apatinib.
  • Condition: Patients with Unresectable and Relapsed Soft-Tissue Sarcoma (STS) in Japan
  • Journal: Cancer
  • Treatment Used: Trabectedin
  • Number of Patients: 140
  • Published —
This study investigated the effectiveness and safety through postmarketing surveillance of trabectedin in patients with unresectable and relapsed soft-tissue sarcomas (STSs).
  • Condition: Guillain-Barre Syndrome in Patients with Synovial Sarcoma (SS)
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: NY-ESO-1 Reactive T-Cell Receptor
  • Number of Patients: 2
  • Published —
This study reported on the development and management of Guillain-Barre syndrome in patients with synovial sarcoma who received NY-ESO-1c259 T-cells.
  • Condition: Synovial Sarcoma (SS)
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: Adoptive Transfer of NY-ESO-1 SPEAR T Cells
  • Number of Patients: 42
  • Published —
These studies addressed the immunological mechanisms of response and resistance in patients with synovial sarcoma (SS) treated with NY-ESO-1 SPEAR T-cells.
  • Condition: Malignant tenosynovial giant cell tumor
  • Journal: Anti-cancer drugs
  • Treatment Used: Chemotherapy and tyrosine-kinase inhibitors
  • Number of Patients: 0
  • Published —
The study researched multiple whole body treatments options for malignant tenosynovial giant cell tumor.
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