Transthyretin AmyloidosisSymptoms, Doctors, Treatments, Advances & More
Learn About Transthyretin Amyloidosis
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Brigham And Women's Hospital
Rodney Falk is a Cardiologist practicing medicine in Boston,, Massachusetts. Dr. Falk is rated as an Elite provider by MediFind in the treatment of Transthyretin Amyloidosis. He is also highly rated in 12 other conditions, according to our data. His clinical expertise encompasses Cardiac Amyloidosis, Primary Amyloidosis, Transthyretin Amyloidosis, Heart Transplant, and Cardiac Ablation.
Cleveland Clinic Main Campus
Mazen Hanna is a Cardiologist practicing medicine in Cleveland, Ohio. He has been practicing medicine for over 33 years. Dr. Hanna is rated as an Elite provider by MediFind in the treatment of Transthyretin Amyloidosis. He is also highly rated in 18 other conditions, according to our data. His clinical expertise encompasses Cardiac Amyloidosis, Transthyretin Amyloid Cardiomyopathy, Primary Amyloidosis, Heart Transplant, and Tenotomy.
Johns Hopkins Bayview Medical Center
Dr. Michael Polydefkis focuses on neuromuscular diseases, particularly peripheral nerve diseases. He has a special interest in diabetic and HIV-associated peripheral neuropathy. His expertise includes nerve conduction studies, electromyography and nerve, skin and muscle biopsy reading. Dr. Michael Polydefkis received his medical degree from The Johns Hopkins University School of Medicine. He then became a Howard Hughes Medical Institute research fellow before returning to Johns Hopkins to complete an internship and residency in internal medicine, residency in neurology and a fellowship in neuromuscular diseases. Dr. Polydefkis is rated as an Elite provider by MediFind in the treatment of Transthyretin Amyloidosis. He is also highly rated in 17 other conditions, according to our data. His clinical expertise encompasses Transthyretin Amyloidosis, Familial Transthyretin Amyloidosis, Primary Amyloidosis, and Peripheral Neuropathy.
Summary: Transthyretin amyloidosis (ATTR) is an underdiagnosed condition that can present early as carpal tunnel syndrome, sometimes preceding cardiac involvement by several years. The recent emergence of new treatments underscores the importance of early diagnosis. Synovial biopsy performed during open carpal tunnel surgery is considered the gold standard for local screening, but it is less accessible, mo...
Summary: Transthyretin (TTR) is a protein made by the liver that helps transport thyroid hormone and vitamin A in the blood. In some people, this protein breaks down and forms harmful clumps called amyloid. TTR amyloid gets deposited in the heart wall and stops it from pumping blood properly, which may lead to heart failure. The breakage in TTR protein can be age-related (wild-type ATTR-CM), or genetic (va...