Clinical Study Evaluating the Efficacy and Safety of Alpha-lipoic Acid in Patients With Ulcerative Colitis Treated With Mesalamine
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims at evaluating the efficacy and safety of alpha-lipoic acid as adjuvant therapy to mesalamine in patients with mild to moderate ulcerative colitis due to its effect as anti-oxidant and anti-inflammatory drug which can help to improve disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age ≥18 years old.
• Both male and female sex.
• Newly diagnosed patients with active mild and moderate ulcerative colitis according to American College of Gastroenterology (ACG) Clinical Guideline for diagnosing Ulcerative Colitis in Adults.26
• Patients treated with 5-aminosalisylic acid (mesalamine).
Locations
Other Locations
Egypt
Tanat university hospital
RECRUITING
Tanta
Contact Information
Primary
Ahmed Farouk
ahmed.farouk.pharmacist@gmail.com
+201067988063
Time Frame
Start Date: 2023-10-01
Estimated Completion Date: 2025-04-01
Participants
Target number of participants: 60
Treatments
Placebo_comparator: Group (Placebo)
(Placepo group; n=30) which will receive mesalamine 1000 mg three times daily plus placebo once daily
Active_comparator: Group (Alpha lipoic acid)
(Alpha-lipoic acid group; n=30) which will receive mesalamine 1000 mg three times daily plus alpha-lipoic acid 600 mg
Related Therapeutic Areas
Sponsors
Leads: Tanta University