Texture and Color Enhancement Imaging (TXI) for Real-time Prediction of Histologic Changes in Patients With Inflammatory Bowel Diseases: a Comparison of White Light Endoscopy (WLE) Versus TXI
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Histologically confirmed inflammatory bowel disease (ulcerative colitis or Crohn\'s disease)
• Age ≥ 18 years
Locations
Other Locations
Germany
Ulm University Hospital
RECRUITING
Ulm
Contact Information
Primary
Benjamin Michael Walter, Prof. Dr. med.
benjamin.walter@uniklinik-ulm.de
+497315000
Backup
Anna Melzer, Dr. med.
anna.melzer@uniklinik-ulm.de
Time Frame
Start Date: 2024-05-08
Estimated Completion Date: 2025-09
Participants
Target number of participants: 80
Treatments
Experimental: TXI mode vs. WLE mode
Use of TXI mode vs. WLE mode for evaluating the degree of inflammation during ileocolonoscopy. Both endoscopy modes are used during the same ileocolonoscopy on the same patient. Photo documentation is taken in both modes.
Related Therapeutic Areas
Sponsors
Leads: University of Ulm