Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism: A Multicenter, Randomized Trial
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is a prospective, multicenter, randomized clinical trial aimed to compare the impact of three AVS diagnostic strategies on the clinical outcomes of patients with primary aldosteronism. The strategies include sequential combined AVS (non-ACTH-stimulated followed by ACTH-stimulated AVS), non- ACTH-stimulated AVS alone, and ACTH-stimulated AVS alone. The findings of this study will provide critical evidence for the clinical practice standards of AVS.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
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• Fully understand the study process, voluntarily agree to participate, and sign informed consent.
• Diagnosed with primary aldosteronism. # Age 18-70 years with hypertension, any sex.
Locations
Other Locations
China
The First Affilated Hospital of Chongqing Medical University
RECRUITING
Chongqing
Contact Information
Primary
Shumin Yang
ysm@hospital.cqmu.edu.cn
+86 023-89011552
Time Frame
Start Date: 2025-12-25
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 456
Treatments
Experimental: sequential combined AVS
non-ACTH-stimulated followed by ACTH-stimulated AVS
No_intervention: non-ACTH-stimulated AVS
non-ACTH-stimulated AVS
No_intervention: ACTH-stimulated AVS
ACTH-stimulated AVS
Related Therapeutic Areas
Sponsors
Collaborators: The People's Hospital of Chuxiong Yi Autonomous Prefecture, The First Affiliated Hospital of Nanchang University, First Affiliated Hospital of Kunming Medical University
Leads: Shumin Yang