Exercise Effects on Adipose Tissue Structure and Function

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:

• Age: 18-40

• Body Mass Index: 27-45 kg/m2

• No regularly planned exercise/physical activity for at least 6 months

• Women must have regularly occurring menses and must be premenopausal

Locations
United States
Michigan
University of Michigan
RECRUITING
Ann Arbor
Contact Information
Primary
Suzette Howton
smlstudies@umich.edu
734-647-9850
Time Frame
Start Date: 2021-03-01
Estimated Completion Date: 2030-03-01
Participants
Target number of participants: 46
Treatments
Experimental: Exercise
This exercise prescription represents a common or conventional form of physical activity (e.g., moderate/brisk walking). If assigned to this group, participants will perform 45 minutes of moderate intensity continuous steady-state exercise at 70% maximal heart rate (HRmax) to expend 250 calories 4 days per week.
Experimental: No exercise
Subjects assigned to this group are to remain sedentary (no planned physical exercise) throughout the duration of the study.
Related Therapeutic Areas
Sponsors
Leads: University of Michigan

This content was sourced from clinicaltrials.gov