The Metabolic Impact of Intermittent Carbohydrate Restriction in Individuals With Type 2 Diabetes
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The primary aim of this randomized cross-over intervention study is to investigate the effect of four weeks of intermittent carbohydrate restriction (alternating between two days of normal dietary intake and two days of carbohydrate restriction to 70-90 grams) on 24-hour average sensor glucose in individuals with type 2 diabetes compared with a four-week control period with normal dietary intake.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 35
Maximum Age: 75
Healthy Volunteers: f
View:
• Men or women
• 35-75 years old
• BMI \>27 kg/m2
• Known type 2 diabetes in stable glucose lowering therapy (for three months) or with HbA1c \>48 mmol/mol if no glucose lowering therapy
Locations
Other Locations
Denmark
Department of Endocrinology, Hvidovre Hospital
RECRUITING
Hvidovre
Contact Information
Primary
Amanda Schaufuss, MSc
amanda.schaufuss@regionh.dk
+4530270261
Time Frame
Start Date: 2024-01-03
Estimated Completion Date: 2025-09-01
Participants
Target number of participants: 14
Treatments
Experimental: Intermittent carbohydrate restriction
Four weeks of intermittent carbohydrate restriction: a dietary regime alternating between two days of restricting carbohydrate intake to 70-90 grams, while energy intake is ad libitum, from fat- and protein-containing foods, and two days of non-restricted diet.
No_intervention: Control arm
Four weeks of free-living with no dietary restrictions.
Related Therapeutic Areas
Sponsors
Collaborators: University of Copenhagen, Danish Research Centre for Magnetic Resonance
Leads: Hvidovre University Hospital