Multicenter Prospective Cohort of Kidney Biopsy for Glomerular Disease Research

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

Glomerulonephritis (GN) generates an enormous individual and social economic burden. However, the therapeutic options are largely based on clinical and pathological parameters and the individual response to therapy or prognosis is uncertain. Recently, along with advances in molecular analysis and computational bioinformatics, genomic data from human renal biopsies could provide a strong foundation for the future of precision medicine in nephrology. In response to a request for applications by the Ministry of Health and Welfare of Korea for the creation of Clinical Research Registry, multi-center N network has been established for prospective cohort with kidney biopsy samples (KORNERSTONE). Through this Network the investigators hope to understand the fundamental biology of glomerulonephritis and aim to bank long-term observational data and corresponding biological data including genomic data from kidney tissues, and kidney pathologic data which is digitalized This database is archived to a web-based platform to access easily and further enrich for researchers.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

⁃ Patient suspected of glomerular disease who received kidney biopsy in participating university medical centers

• Children (age\<18 years) also included

Locations
Other Locations
Republic of Korea
KangWon National University Hospital
RECRUITING
Chuncheon
Keimyung University Dongsan Medical Center
RECRUITING
Daegu
Chung-Ang University Hosptial
RECRUITING
Seoul
Seoul National University Hospital
RECRUITING
Seoul
Severance Hospital
RECRUITING
Seoul
SMG-SNU Boramae Medical Center
RECRUITING
Seoul
Contact Information
Primary
Yong Chul Kim, MD,PhD.
imyongkim@gmail.com
+82-10-8874-7429
Backup
Eunyoung Kim
irish-key@nate.com
+82-2-6072-5188
Time Frame
Start Date: 2019-05-01
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 3000
Treatments
KORNERSTONE
Glomerulonephritis (GN) such as Minimal change disease (MCD), focal segmental glomerulosclerosis (FSGS), Membranous nephropathy (MN), and Immunoglobulin A nephropathy (IgAN)~Participants enrolled in KORNERSTONE with a biopsy proven GN.~Eligible participants must be scheduled for a clinically indicated renal biopsy.
Authors
Ho Jun Chin, Jong Cheol Jeong
Sponsors
Collaborators: Seoul National University Bundang Hospital, Chung-Ang University Hosptial, Chung-Ang University College of Medicine, SMG-SNU Boramae Medical Center, KangWon National University Hospital, Ministry of Health & Welfare, Korea, Severance Hospital, Keimyung University Dongsan Medical Center
Leads: Seoul National University Hospital

This content was sourced from clinicaltrials.gov