Vaginal cancer is cancer of the vagina, a female reproductive organ.
Vaginal cancer; Cancer - vagina; Tumor - vaginal
Most vaginal cancers occur when another cancer, such as cervical, vulvar, or endometrial cancer, spreads. This is called secondary vaginal cancer.
Cancer that starts in the vagina is called primary vaginal cancer. This type of cancer is rare. Most primary vaginal cancers start in skin-like cells called squamous cells. This cancer is known as squamous cell carcinoma. The other types include:
The cause of squamous cell carcinoma of the vagina is unknown. But a history of cervical cancer is common in women with squamous cell carcinoma of the vagina. So it may be associated with human papilloma virus (HPV) infection.
Most women with squamous cell cancer of the vagina are over 50.
Adenocarcinoma of the vagina tends to affect younger women. The average age at which this cancer is diagnosed is 19. Women whose mothers took the medicine diethylstilbestrol (DES) to prevent miscarriages during the first 3 months of pregnancy are more likely to develop vaginal adenocarcinoma.
Sarcoma of the vagina is a rare cancer that mainly occurs in infancy and early childhood.
Symptoms of vaginal cancer can include any of the following:
Some women have no symptoms.
Treatment of vaginal cancer depends on:
Surgery is sometimes used if the cancer is small and located at the upper part of the vagina. Most women are treated with radiation. If the tumor is cervical cancer that has spread to the vagina, radiation and chemotherapy are both given.
Sarcoma may be treated with a combination of chemotherapy, surgery, and radiation.
Ruchi Garg is a Gynecologic Oncologist in Leesburg, Virginia. Dr. Garg has been practicing medicine for over 22 years and is rated as a Distinguished doctor by MediFind in the treatment of Vaginal Cancer. She is also highly rated in 12 other conditions, according to our data. Her top areas of expertise are Endometrial Cancer, Endometrial Stromal Sarcoma, Malignant Mixed Mullerian Tumor, Oophorectomy, and Hysterectomy. Dr. Garg is currently accepting new patients.
Bruce Kressel is a Hematologist Oncology specialist and a Hematologist in Washington, Washington, D.c.. Dr. Kressel has been practicing medicine for over 50 years and is rated as an Advanced doctor by MediFind in the treatment of Vaginal Cancer. He is also highly rated in 66 other conditions, according to our data. His top areas of expertise are Essential Thrombocythemia, Non-Hodgkin Lymphoma, Gastric Lymphoma, Testicular Yolk Sac Tumor, and Splenectomy. Dr. Kressel is currently accepting new patients.
Annette Bicher is a Gynecologic Oncologist in Fairfax, Virginia. Dr. Bicher has been practicing medicine for over 36 years and is rated as an Advanced doctor by MediFind in the treatment of Vaginal Cancer. She is also highly rated in 20 other conditions, according to our data. Her top areas of expertise are Malignant Mixed Mullerian Tumor, Testicular Yolk Sac Tumor, Virilizing Ovarian Tumor, Hernia Surgery, and Gastrostomy. Dr. Bicher is currently accepting new patients.
You can ease the stress of illness by joining a support group whose members share common experiences and problems.
The outlook for women with vaginal cancer depends on the size and the stage of disease and the specific type of tumor.
Vaginal cancer may spread to other areas of the body. Complications can occur from radiation, surgery, and chemotherapy.
Call for an appointment with your health care provider if:
There are no definite ways to prevent this cancer.
The HPV vaccine is approved to help prevent cervical cancer. This vaccine may also decrease the risk of getting some other HPV-associated cancers, such as vaginal cancer. You can increase your chance of early detection by getting regular pelvic examinations and Pap smears.
Summary: This research is being done to evaluate multimodality imaging, including magnetic resonance imaging-guided therapy (MRT), as a possible treatment for gynecologic cancers. The therapy takes place in the Department of Radiation Oncology at the Johns Hopkins SKCCC. The purpose of this study is to investigate the ability of MRI to successfully guide the placement of the brachytherapy applicator necess...
Background: Often, metastatic human papillomavirus (HPV) associated cancers cannot be cured. They also do not respond well to treatment. Some forms of colon cancer also have poor responses to treatment. Researchers want to see if a new drug treatment can help people with these types of cancers.
Published Date: January 01, 2022
Published By: Howard Goodman, MD, Gynecologic Oncology, Florida Cancer Specialists & Research Institute, West Palm Beach, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Bodurka DC, Frumovitz M. Malignant diseases of the vagina: intraepithelial neoplasia, carcinoma, sarcoma. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 31.
Jhingran A, Russell AH, Seiden MV, et al. Cancers of the cervix, vulva, and vagina. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 84.
PDQ Adult Treatment Editorial Board. Vaginal Cancer Treatment (PDQ®): Health Professional Version. 2022 Feb 24. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002–. PMID: 26389242 pubmed.ncbi.nlm.nih.gov/26389242/.