Clinical Outcomes and Quality of Life in Patients With Locally Advanced Vulvovaginal Cancers: Ambispective Registration Study.

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The vaginal cancers are responsible for 2% of gynecological cancer while vulvar cancers account for 4 % of gynecological cancers. HPV 16 and 33 are most prevalent in vaginal cancers and account for more than half of cases HPV related vaginal cancer. However, adeqaute information is not there. Similarly, structured QOL data is not available for India. Therefore, in the proposed study we will like to systematically evaluate the patterns of relapse and disease outcomes in patients with vulvovaginal cancer treated with radiation (+/- chemotherapy). The therapeutic research in vulvo-vaginal cancers has been relatively slow and such structured registration databases can allow analysis of large number of patients to report on acute and late effect of treatment outcomes using CTCAE and QOL (EORTC QLQ C-30 and VU-34) in rare cancers. We hope that we will get help in identifying thrust areas for future research including prospective interventional trials through this study.

Eligibility
Participation Requirements
Sex: Female
Healthy Volunteers: f
View:

• All patients diagnosed with vulvo- vaginal cancer.

• Patients treated with Radiation+/- chemotherapy+/-surgery from January 1, 2019- December 31, 2023.

Locations
Other Locations
India
Tata Memorial Hospital
RECRUITING
Mumbai
Contact Information
Primary
Dr. Supriya Chopra
supriyasastri@gmail.com
+022-68735000
Time Frame
Start Date: 2021-10-30
Estimated Completion Date: 2026-10
Participants
Target number of participants: 200
Treatments
Cohort A
n= 80 Retrospective Cohort
Cohort B
n=120 Prospective Cohort
Related Therapeutic Areas
Sponsors
Leads: Tata Memorial Hospital

This content was sourced from clinicaltrials.gov