PET Fibrin Imaging of DVT and PE
Who is this study for? Patients with Venous Thromboembolism
What treatments are being studied? 64Cu-FBP8+PET-CT Imaging
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY
This study aims to investigate a novel positron emission tomography(PET)-probe for imaging of fresh intravascular blood clots in pulmonary embolism (PE) and deep venous thrombosis (DVT).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• 18 years of age or older with a clinically significant pulmonary embolus (PE) confirmed by a filling defect in CT angiography (CTA), and
• Subjects must receive the radiotracer injection within 72 hours of their diagnosis.
Locations
United States
Massachusetts
Massachusetts General Hospital
RECRUITING
Boston
Contact Information
Primary
Tilo Winkler, PhD
twinkler@mgh.harvard.edu
617-724-4083
Backup
Mamary T Kone, MD, MPH
mkone@mgh.harvard.edu
617-726-1082
Time Frame
Start Date: 2019-05-13
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 80
Treatments
Experimental: Acute pulmonary embolism
Subjects will receive 64Cu-FBP8 and undergo PET-CT imaging.
Related Therapeutic Areas
Sponsors
Leads: Peter Caravan
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)