Prospective Randomized Controlled Study of Ropivacaine-Poloxamer 407 Based Gel Application and TAP Block for Postoperative Pain Management Following Laparoscopic/Robotic Gastrectomy
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to determine whether Ropivacaine-Poloxamer 407 hydrogel provides non-inferior pain control compared to TAP block for patients undergoing minimally invasive gastrectomy. The results will guide postoperative pain management practices and enhance recovery protocols for gastric cancer surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Healthy Volunteers: f
View:
• Patients with a histologically confirmed diagnosis of gastric adenocarcinoma prior to surgery.
• Patients who have undergone a complete surgical resection (R0 resection).
• Patients with an ASA (American Society of Anesthesiologists) score of 3 or below.
• Patients aged 20 years or older.
• Patients who have undergone laparoscopic or robotic gastrectomy
Locations
Other Locations
Republic of Korea
Gangnam Severance Hospital
RECRUITING
Seoul
Contact Information
Primary
In Gyu Kwon
gsirb@yuhs.ac
82-2-2019-4601
Time Frame
Start Date: 2025-02-01
Estimated Completion Date: 2026-03-31
Participants
Target number of participants: 134
Treatments
Experimental: Ropivacaine-Poloxamer 407 hydrogel group
Patients withRopivacaine-Poloxamer 407 hydrogel applied to the peritoneal and subcutaneous layers at the incision site.
Active_comparator: TAP block group
Patients with Ultrasound-guided subcostal TAP block with 0.375% ropivacaine (15 mL per side).
Related Therapeutic Areas
Sponsors
Leads: Gangnam Severance Hospital