Department of Otolaryngology Head Neck Surg

Status: Unknown
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Recruited patients are divided into two arms depending on laryngeal carcinoma's T1 and T2 stages. Two interventions were undergone, including transoral endoscopic laser cordectomy and open partial horizontal laryngectomy (OPHL). During the pre-and post-operative time, patients performed measurements of swallowing function, including direct subglottic pressure, Eating Assessment Tool-10(EAT-10) questionnaire, swallowing ability to different textures, and fiberoptic evaluation of swallowing(FEES). Patients undergo subglottic pressure measurement and swallowing function evaluation three times: 3-7 days, two months, and six months after surgery. Patients also performed measurement voice acoustic analysis and subjective assessment one-day pre-operation and six months post-operation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Age: 18-80 years

• Surgical treatment by open partial horizontal laryngectomy type I or II and transoral laser cordectomy for squamous cell carcinoma

• Availability of clinical data

• Validity of normal swallowing of thin liquids

Locations
Other Locations
China
Guangdong Provincial People's hospital
RECRUITING
Guangzhou
Contact Information
Primary
Pingjiang Ge, M.D.
gepingjiang@aliyun.com
+8613751753465
Time Frame
Start Date: 2023-01-03
Completion Date: 2025-12-01
Participants
Target number of participants: 50
Treatments
Active_comparator: Supraglottic and glottic T2 laryngeal carcinoma
The open partial horizontal laryngectomy was underwent in patients with supraglottic or glottic laryngeal carcinoma in T2
Active_comparator: Supraglottic and glottic T1 laryngeal carcinoma
The transoral endoscopic laser cordectomy was underwent in patients with supraglottic or glottic laryngeal carcinoma in T1
Sponsors
Leads: Guangdong Provincial People's Hospital

This content was sourced from clinicaltrials.gov