Comprehensive Hematological and Biochemical Comparison of Low-Dose Liposomal Iron Versus Standard-Dose Conventional Oral Iron in Iron Deficiency Anemia Following Sleeve Gastrectomy: A Prospective, Randomized Clinical Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Low-dose liposomal iron (17-34 mg elemental/day) was compared with standard conventional oral iron (100-200mg elemental/day) in the treatment of iron deficiency anemia following sleeve gastrectomy. Liposomal iron provided superior hematological improvement and gastrointestinal tolerance.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Age between 18 and 65 years
• History of laparoscopic sleeve gastrectomy performed at least 6 months prior to enrollment
• Diagnosis of iron deficiency anemia, defined as:
• Hemoglobin \<12 g/dL in women or \<13 g/dL in men, and
• Serum ferritin \<30 ng/mL or transferrin saturation (TSAT) \<20%
• Mild to moderate anemia (hemoglobin ≥9 g/dL)
• Ability to take and swallow oral medications
Locations
Other Locations
Turkey
Goztepe Prof.Dr. Suleyyman Yalçın City Hospital
RECRUITING
Istanbul
Contact Information
Primary
Medeni Sermet, assoc.prof
sermetmedeni@gmail.com
+905072367020
Time Frame
Start Date: 2025-09-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 70
Treatments
Experimental: Arm 1 Title: Liposomal Iron (Group LD)
Participants with iron deficiency anemia after laparoscopic sleeve gastrectomy receiving oral liposomal iron.
Active_comparator: Arm 2 Title: Conventional Iron (Group KD)
Participants with iron deficiency anemia after laparoscopic sleeve gastrectomy receiving conventional oral ferrous iron preparations.
Related Therapeutic Areas
Sponsors
Leads: Medeni Şermet