The Role of Adipose Tissue in Adaptive Responses to Exercise
Status: Recruiting
Location: See location...
Intervention Type: Procedure, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this research is to determine how exercise affects fat (adipose) tissue and how changes to adipose tissue that occur during and after exercise might improve health in aging and obesity.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
Healthy Volunteers: t
View:
• Adults between the ages of 18-35 OR 65-85.
• BMI 18.5 kg/m2 - 40 kg/m2
• Weight stable (≥ 3 months)
• Generally healthy
Locations
United States
Minnesota
Mayo Clinic
RECRUITING
Rochester
Contact Information
Primary
Rachel Passehl
Passehl.Rachel@mayo.edu
507-255-8112
Time Frame
Start Date: 2023-11-09
Estimated Completion Date: 2026-10
Participants
Target number of participants: 60
Treatments
Experimental: Older adults with obesity
Participants with obesity as determined by the principal investigator and aged 65-85 years will have an adipose tissue biopsy taken from the abdomen before and after exercise.
Experimental: Older adults without obesity
Participants with obesity as determined by the principal investigator and aged 65-85 years will have an adipose tissue biopsy taken from the abdomen before and after exercise.
Experimental: Young adults with obesity
Participants with obesity as determined by the principal investigator and aged 18-35 years will have an adipose tissue biopsy taken from the abdomen before and after exercise.
Experimental: Young adults without obesity
Participants with obesity as determined by the principal investigator and aged 18-35 years will have an adipose tissue biopsy taken from the abdomen before and after exercise.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Leads: Mayo Clinic