As a physician scientist in the hematological malignancies and stem cell transplantation division with Sidney Kimmel Comprehensive Cancer Center at the Johns Hopkins, my focus is on the various aspects of cellular therapy in the treatment of hematological malignancies. My primary research focus is to develop strategies to prevent relapse of hematological malignancies following allogeneic stem cell transplantation. Additionally, I serve as the director of the adult CAR T program for hematological malignancies as we grow our CAR T program to help patients with advanced hematological malignancies. My academic interest in this space lies in studying the aspects of toxicity of CAR T cell therapy with an aim to improve long term outcomes in these patients. Among hematological malignancies, myeloproliferative disorders are my area of interest and I work to study newer drugs in early phase of development and also its treatment using allogeneic stem cell transplantation. Patient appointments: 410-955-8893. Dr. Jain is rated as a Distinguished provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Myelofibrosis, Myeloproliferative Neoplasms (MPN), Splenomegaly, Bone Marrow Transplant, and Splenectomy.

William Houck is an Oncologist in Baltimore, Maryland. Dr. Houck is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Paget Disease of the Breast, Lung Cancer, Chronic B-Cell Leukemia (CBCL), and Chronic Lymphocytic Leukemia (CLL).

Dr. DeZern is a Professor of Oncology and Medicine at The Johns Hopkins University School of Medicine. She is active in the Division of Hematology Malignancies, Leukemia Program at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. Dr. DeZern has expertise in aplastic anemia, myelodysplastic syndromes, paroxysmal nocturnal hemoglobinuria, acute myeloid leukemia, and bone marrow transplantation. Dr. DeZern received her medical degree at The Johns Hopkins University School of Medicine. She completed a residency in internal medicine at Johns Hopkins, followed by fellowships in medical oncology and hematology, as well as obtained a Masters in Clinical Investigations at the Bloomberg School of Public health. Dr. DeZern is a member of the American Society of Hematology, the American Society of Clinical Oncology, and the American Society for Transplantation and Cellular Therapy. Dr. DeZern’s principle research activities consist of designing and conducting clinical trials that test investigational new therapies and approaches in the treatment of bone marrow failure (aplastic anemia and myelodysplastic syndromes). She has specific expertise in the use of alternative donor bone marrow transplantation in patients with severe aplastic anemia and trials of novel therapeutics for patients with myelodysplastic syndromes. Additionally, she has taken a rigorous approach to the study of diagnostics and supportive case (such as transfusion practices) in these patient populations. She is or has been the Principal Investigator for a number of multicenter trials in collaboration with the MDS Clinical Research Consortium, the Eastern Co-operative Oncology Group (ECOG)-ACRIN and now the Bone Marrow Trials Clinical Trials Network (BMTCTN). She is the Study Chair for the multi-site BMTCTN study (CHAMP) investigating the role of haploidentical donor transplantation using post-transplantation cyclophosphamide in patients with relapsed several aplastic anemia. Dr. DeZern is the local PI as well as the Deputy Chair for The National MDS Study, a collaborative natural history study of the NHLBI and the NCI. As a clinical investigator with a focus on translation of novel treatments to the clinic, Dr. DeZern’s goal is to improve outcomes for patients with bone marrow failure at the bedside and in her research environment. Dr. Dezern is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML), Acute Myeloid Leukemia (AML), Bone Marrow Transplant, and Bone Marrow Aspiration.

Dr. Nara Lygia De Macena Sobreira is an assistant professor at the McKusick-Nathans Department of Genetic Medicine at Johns Hopkins University School of Medicine. Her area of expertise is rare Mendelian phenotypes, analysis of next-generation sequencing, and functional testing of candidate causative variants. She earned her M.D. at the University of Pernambuco in Brazil. She finished her Ph.D. in Human Genetics at Johns Hopkins followed by a one-year postdoc also at Johns Hopkins School of Medicine. During her Ph.D., she worked with Dr. David Valle using next-generation sequencing to elucidate the molecular basis of rare Mendelian phenotypes and in 2010 she discovered PTPN11 as the gene responsible for metachondromatosis by using whole-genome sequencing. She completed residencies in clinical genetics at both Universidade Federal de Sao Paulo and Johns Hopkins. Her main clinical and research focus is on identifying the genetic bases of rare phenotypes, mainly, phenotypes associated with cartilage tumors and vascular anomalies (including Ollier disease and Maffucci syndrome), and on understanding the physiopathology of these phenotypes to identify pharmacological strategies to treat them. She has worked extensively on developing strategies to better analyze the variants identified by next-generation sequencing and on novel strategies for data sharing. She participated on the development of PhenoDB, a phenotypic and genomic database, and created PhenoDB Variant Analysis Tool used worldwide. She is also one of the creators of GeneMatcher, VariantMatcher, and one of the co-founders of the Matchmaker Exchange, all intended to share next-generation sequencing data. She has also worked extensively on functional studies that evaluate the possible pathogenic effects of the candidate causative variants. Recent News Articles and Media Coverage Living the Hopkins Mission Honorees, Johns Hopkins Medicine Successes in Characterizing Genes through GeneMatcher with Nara L. M. Sobreira, MD, PhD, Ambry Genetics (April 30, 2018) Enfermedades raras: el desafio es encontrar otros pacientes que tienen el mismo mal, Lun (26 de septiembre de 2019) 2021 Science Writers' Boot Camp, Johns Hopkins Medicine (June 7, 2021) Making the Perfect Match, Johns Hopkins Medicine (February 1, 2020). Dr. De Macena Sobreira is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Spondyloepimetaphyseal Dysplasia Strudwick Type, Greenberg Dysplasia, Blepharophimosis, and Early Infantile Epileptic Encephalopathy.

Dr. Ada Hamosh is the Dr. Frank V. Sutland Professor of Pediatric Genetics in the Departments of Genetic Medicine and Pediatrics. Since 2002, she has served as clinical director of the McKusick-Nathans Institute of Genetic Medicine, now Department of Genetic Medicine and scientific director of the Online Mendelian Inheritance in Man® (OMIM), a catalog of more than 16,800 human genes and genetic disorders created by Dr. Victor A. McKusick. Her research centers the molecular basis of Mendelian disorders, the integration of genetics into clinical practice and the diagnosis and management of inborn errors of metabolism. Dr. Hamosh earned a bachelor’s degree in biology from Wesleyan University, a medical degree from Georgetown University School of Medicine and a master’s of public health from Johns Hopkins University School of Public Health. She later completed a fellowship in medical and biochemical genetics from the Johns Hopkins School of Medicine, before joining the Johns Hopkins faculty in 1992. Dr. Hamosh began her genetics career focusing on cystic fibrosis, serving as coordinator of the International Cystic Fibrosis Genotype-Phenotype Consortium. She served as chair of the Maryland State Advisory Council for Hereditary & Congenital Disorders from 2001-2009, during which time she also served on the executive committee of the Genetic Counseling Training Program, run by Johns Hopkins University and the National Human Genome Research Institute. Dr. Hamosh has authored more than 128 publications on a variety of topics. In addition, she is a member of 16 professional associations and advisory committees including the American Society of Human Genetics, the Steering Committee of the Global Alliance for Genomics and Health, and the executive board of the Human Genome Organization, of which she will be President from 2023-2025. Dr. Hamosh was recognized in Baltimore magazine as one of the region’s top doctors in 2013, and 2016-2020. Dr. Hamosh is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Methylmalonic Acidemia, Maple Syrup Urine Disease, Ornithine Transcarbamylase Deficiency, Phenylketonuria (PKU), and Deep Brain Stimulation.

Dr. Richard Southard’s specialty is in pediatric radiology, with more than 25 years of experience in private practice and hospital settings. He joins Johns Hopkins from Phoenix Children’s Hospital, where he is vice chief of Radiology Operations. Previously, he served as a pediatric radiologist, partner and president of Radiology Consultants North Dallas, a Texas-based private practice group. He earned his medical degree from The Ohio State University before going on to an internship and residency in pediatric medicine at Nationwide Children’s Hospital, followed by a diagnostic radiology residency at The University of Pittsburgh Medical Center and fellowship in pediatric radiology at Pittsburgh Children’s Hospital. Dr. Southard’s research has focused on CT radiation dose reduction, imaging of congenital heart disease, implementation and validation of iterative reconstruction noise reduction techniques and dual-energy spectral CT applications in children. He joined the pediatric radiology faculty in February 2023 and will be working remotely from Arizona. Dr. Southard is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Tracheobronchopathia Osteoplastica, Bronchogenic Cyst, Dextrocardia, and Collins Pope Syndrome.

Dr. David Valle is a professor of pediatrics and ophthalmology at the Johns Hopkins School of Medicine and former director of the Johns Hopkins Department of Genetic Medicine. He also serves as a geneticist for the Johns Hopkins Children’s Center. Dr. Valle holds a bachelor’s degree and medical degree from Duke University. He completed a pediatric residency at Johns Hopkins University before joining the Johns Hopkins faculty. He is interested in the genetic contributions to health and disease. He is the founding director of the Johns Hopkins Center for Inherited Disease Research. Over the years, his laboratory has discovered the genetic causation for more than 20 diseases, including those responsible for inborn errors of metabolism, inherited retinal degeneration, disorders of cellular organelle biogenesis and genetic variations that contribute risk for common disorders such as schizophrenia. Dr. Valle also serves as director of the Predoctoral Training Program in Human Genetics, as well as co-director of the Genes to Society program. He was a 2014 recipient of the annual Victor A. McKusick Leadership Award from the American Society of Human Genetics, which recognizes individuals whose professional achievements have fostered and enriched the development of human genetics as well as its assimilation into the broader context of science, medicine and health. Dr. Valle is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Spondyloepimetaphyseal Dysplasia Strudwick Type, Micrognathia, Urea Cycle Disorders (UCD), and Spondyloepiphyseal Dysplasia Congenita.

Dr. Melissa Leimkuehler is a diagnostic radiologist specializing in cross-sectional body imaging, with more than 15 years of experience in hospital and private practice settings. Dr. Leimkuehler joins Johns Hopkins from Truman Medical Centers in Kansas City, MO, where she was a staff radiologist with an expertise in body imaging. She earned her medical degree from the University of Missouri-Kansas City (UMKC) before going on to an internship there the following year. She also completed her residency at UMKC, serving as chief radiology resident. She went on to a cross-sectional body imaging fellowship at Johns Hopkins University School of Medicine. Dr. Leimkuehler is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Nasal Flaring, Biliary Dyskinesia, Pleurisy, and Visceromegaly.

Dr. Satomi Kawamoto is an Associate Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science. She specializes in computed tomography (CT), ultrasound, and image-guided biopsy. Dr. Kawamoto received her M.D. from Gunma University in Gunma, Japan, and subsequently completed two residencies, one in internal medicine at St. Luke’s International Hospital in Tokyo, and a second in diagnostic radiology at Johns Hopkins. She received a postdoctoral fellowship in cross-sectional imaging at Johns Hopkins, and then joined the Johns Hopkins faculty. Dr. Kawamoto’s research focuses on body CT and biopsy, particularly imaging of the genitourinary and gastrointestinal systems. Dr. Kawamoto is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Neuroendocrine Tumor, Muscle Invasive Bladder Cancer, Cavernous Lymphangioma, Hepato-Pancreato-Biliary Surgery, and Pancreaticoduodenectomy.

Ravin Garg is a Hematologist Oncology specialist and an Oncologist in Baltimore, Maryland. Dr. Garg is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Large-Cell Immunoblastic Lymphoma, Paget Disease of the Breast, Breast Cancer, and Thrombotic Thrombocytopenic Purpura.

Peter Salazar is a Radiologist in Baltimore, Maryland. Dr. Salazar is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are CAPOS Syndrome, Aseptic and Alopecic Nodules of Scalp (AANS), Gallbladder Disease, and Pleural Effusion.

Dr. Amira Hussien is an Instructor in the Johns Hopkins Medicine Department of Radiology and Radiological Science. She received her Bachelor of Medicine, Bachelor of Surgery at Cairo University School of Medicine and completed diagnostic radiology residencies at Cairo University School of Medicine and the University of Rochester Medical Center. Dr. Hussien performed a neuroradiology fellowship and musculoskeletal radiology fellowship at University of Rochester Medical Center. She most recently completed a fellowship at University of Maryland Medical Center. Dr. Hussien is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Pleural Effusion, Pleurisy, Colonic Malakoplakia, and Lung Nodules.

Dr. Alice Goldman is an Associate Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science. She received her medical degree from New York University School of Medicine and completed her radiology fellowship at Mount Sinai Beth Israel Medical Center. Dr. Goldman performed her body imaging fellowship at Yale School of Medicine. Dr. Goldman is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Lymphofollicular Hyperplasia, Mesenchymoma, Undifferentiated Pleomorphic Sarcoma, and Alveolar Soft Part Sarcoma.

Danica Novacic is a primary care provider, practicing in Internal Medicine in Baltimore, Maryland. Dr. Novacic is rated as an Advanced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Splenomegaly, Magnesium Deficiency, Renal Hypomagnesemia Type 2, and Calciphylaxis.

Ann Zimrin is a Hematologist Oncology specialist and a Hematologist in Baltimore, Maryland. Dr. Zimrin is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Thrombocytopenia, Sickle Cell Disease, Hemoglobinopathy, Hemoglobin C Disease, and Splenectomy. Dr. Zimrin is currently accepting new patients.

Karen Song is a Radiologist in Baltimore, Maryland. Dr. Song has been practicing medicine for over 17 years and is rated as an Advanced provider by MediFind in the treatment of Splenomegaly. Her top areas of expertise are Pleurisy, Pleural Effusion, CAPOS Syndrome, and Congenital Coronary Artery Malformation.

Kalyan Paudel is a Radiologist in Baltimore, Maryland. Dr. Paudel is rated as an Advanced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Nasal Flaring, Lymphofollicular Hyperplasia, Splenomegaly, Pleurisy, and Liver Embolization.

Nebiyu Adenaw is a Radiologist in Baltimore, Maryland. Dr. Adenaw is rated as a Distinguished provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Ascites, Splenomegaly, Pleurisy, Bone Marrow Aspiration, and Liver Embolization.

Marvin Feldman is a Hematologist Oncology specialist and a Hematologist in Baltimore, Maryland. Dr. Feldman is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Anal Cancer, Laryngeal Cancer, Familial Colorectal Cancer, and Angiosarcoma.

Sherwin Danaie is a Radiologist and a Cardiologist in Baltimore, Maryland. Dr. Danaie is rated as an Experienced provider by MediFind in the treatment of Splenomegaly. His top areas of expertise are Pleurisy, Gallbladder Disease, Pleural Effusion, and Muscle Invasive Bladder Cancer.