Latest Advances

  • Condition: HIV
  • Journal: The lancet. HIV
  • Treatment Used: Raltegravir or Efavirenz
  • Number of Patients: 802
  • Published —
This study compared the clinical outcome of using raltegravir or efavirenz to treat patients with HIV.
  • Condition: HIV-Exposed Newborn Infants
  • Journal: The Journal of infectious diseases
  • Treatment Used: Broadly Neutralizing Human Immunodeficiency Virus (HIV)-1 Monoclonal Antibody VRC01
  • Number of Patients: 40
  • Published —
This study evaluated the safety and pharmokinetics of a broadly neutralizing human immunodeficiency virus (HIV)-1 monoclonal antibody VRC01 in HIV-exposed newborn infants.
  • Condition: Pregnant Mothers with HIV Infection and Their Neonates
  • Journal: PLoS medicine
  • Treatment Used: Dolutegravir (DTG)
  • Number of Patients: 0
  • Published —
This study assessed the relationship between drug concentrations (pharmacokinetics, PK) of dolutegravir (DTG), including in breastmilk, and the impact on viral suppression when initiated in the third trimester (T3) in pregnant mothers with HIV infection and their neonates.
  • Condition: Growth after HIV-Exposure in Chinese Infants
  • Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
  • Treatment Used: Antiretroviral Drugs: nevirapine (NVP) vs. zidovudine (AZT)
  • Number of Patients: 564
  • Published —
The purpose of this study was to compare the influence of the antiretroviral drugs nevirapine (NVP) versus zidovudine (AZT) on the growth and development of HIV-exposed uninfected infants in China.
  • Condition: Human Immunodeficiency Virus (HIV)-Positive Patients on Combination Antiretroviral Therapy (ART) with Tuberculosis Meningitis (TBM) and Hydrocephalus
  • Journal: World neurosurgery
  • Treatment Used: Ventriculoperitoneal Shunt Surgery (VPS)
  • Number of Patients: 30
  • Published —
This study described the outcome of ventriculoperitoneal shunting (VPS) in patients with tuberculous meningitis (TBM) and hydrocephalus who are HIV positive and receiving antiretroviral therapy (ART).
  • Condition: Pregnant Women with HIV
  • Journal: BMC infectious diseases
  • Treatment Used: Antiretroviral Therapy (ART)
  • Number of Patients: 793
  • Published —
This study evaluated the adverse effects of antiretroviral therapy (HIV treatment that uses a combination of two or more antiretroviral drugs; ART) in pregnant women infected with HIV (a sexually transmitted infection).
  • Condition: Prevention of HIV-1 Transmission Through Breastfeeding
  • Journal: Journal of acquired immune deficiency syndromes (1999)
  • Treatment Used: Maternal Antiretroviral Therapy vs. Infant Nevirapine Prophylaxis
  • Number of Patients: 2431
  • Published —
This study compared the effectiveness of prolonged infant antiretroviral nevirapine (iNVP) prophylaxis versus maternal antiretroviral therapy (mART) for prevention of mother-to-child transmission throughout the breastfeeding period in HIV-1-Infected Women With High CD4 Cell Count.
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