Comparing Neural Responses to Explicit and Subliminal Food Images in EDNOS Patients and Healthy Controls Using fMRI

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Currently, there is not a robust, testable neural model available that sufficiently explains the development and maintenance of anorexia nervosa (AN) a severe, often fatal, adolescent-onset eating disorder. Using state of the art neuroimaging and neuropsychological techniques, our objective is to identify neural mechanisms in the adolescent brain underlying AN. This is of high clinical relevance in as much as it will provide a robust platform for a diagnostic battery so that physicians can identify those who are prone to develop AN at a very early stage of life. The aim of this research plan is: 1) To develop knowledge of cognitive dysfunction in adolescents who have recently been diagnosed with AN, with a battery of cognitive tests during a series of clinical visits. 2) To provide a scientific basis for our knowledge about how the brain of an adolescent with an eating disorder differs from that of a healthy adolescent, by conducting functional and structural magnetic resonance imaging on adolescent females with AN.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 13
Maximum Age: 18
Healthy Volunteers: t
View:

• Females

• Age 13 - 18 yrs

• Right handed

• For controls: BMI within the normal range

• For patients: Be admitted to treatment for an eating disorder

Locations
Other Locations
Sweden
Röntgenavdelningen, Uppsala Academic Hospital
RECRUITING
Uppsala
Contact Information
Primary
Christina Zhukovsky, MMed
christina.zhukovsky@neuro.uu.se
Time Frame
Start Date: 2011-05
Estimated Completion Date: 2027-12
Participants
Target number of participants: 150
Treatments
Eating disorder
Patients currently in treatment for eating disorders.
Healthy Controls
Age- and gender matched healthy controls.
Related Therapeutic Areas
Sponsors
Leads: Uppsala University

This content was sourced from clinicaltrials.gov