Neurocognitive Testing in Long COVID and Postural Tachycardia Syndrome Patients with Normal Saline: a Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with Postural Orthostatic Tachycardia Syndrome (POTS) and Post-Acute Sequelae of COVID (PASC, or Long COVID) experience cognitive dysfunction. The investigators will test the hypothesis that 999 mL of IV saline will improve cognitive function in patients with POTS and Long COVID compared to placebo (50 mL of saline).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:

• Patients with diagnosis of Long COVID

• SARS-COV2 test positive

• Symptoms \> 12 weeks post COVID

• Subjective complaint of 'brain fog or cognitive dysfunction

• Patients with diagnosis of Postural Orthostatic Syndrome (POTS) from the Calgary Autonomic Investigation and Management Clinic

• Subjective complaint of 'brain fog or cognitive impairment

• Healthy participants

• Without POTS or brain fog

• Age 18 to 60 years

• Female and Male

• Able to give an informed consent

Locations
Other Locations
Canada
University of Calgary
RECRUITING
Calgary
Contact Information
Primary
Satish R Raj, MD MSCI
autonomic.research@ucalgary.ca
(403)210-6152
Backup
Rasha Hamzeh, RN
autonomic.research@ucalgary.ca
Time Frame
Start Date: 2024-09-19
Estimated Completion Date: 2029-12-31
Participants
Target number of participants: 100
Treatments
Experimental: 999 mL normal Saline
999 mL of normal saline infused intravenously.
Placebo_comparator: 50 mL normal Saline
50 mL of normal saline infused intravenously.
Sponsors
Leads: University of Calgary

This content was sourced from clinicaltrials.gov