A Multi-center, Prospective, Compared, Randomized, Evaluator-blinded, Pilot Study to Evaluate the Effectiveness of Digital Therapeutics 'NDTx-02' on Executive Function in Children and Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD)

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral, Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this study is to explore the preliminary safety and effectiveness of the digital therapeutic device 'NDTx-02' in supporting improvements of executive function in children and adolescents diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 12
Healthy Volunteers: f
View:

• Children and adolescents aged 5 to 12 years at the time of screening

• Diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) or Autism Spectrum Disorder (ASD)\* by a psychiatrist according to DSM-5 diagnostic criteria

• \*For ASD, diagnosis can be supported by the Autism Diagnostic Interview-Revised (ADI-R) or the Autism Diagnostic Observation Schedule (ADOS), either version 1 or 2

• Full-Scale Intelligence Quotient (FSIQ) of 65 or higher

• Able to use the 'NDTx-02' installed on a tablet, alone or with the assistance of a guardian

• Able to comply with the recommended application schedule for the investigational device (6 weeks, 30 sessions, 5 times per week)

• Agree not to add or change any treatment/education/rehabilitation programs or medications, including Applied Behavior Analysis (ABA) or cognitive therapy, during the study period (continuation of pre-existing TAU \[Treatment-As-Usual\] is allowed)

• Participant and parent (or legal guardian) voluntarily decide to join the trial and provide written informed consent

• Participants willing to comply with the clinical trial procedures

Locations
Other Locations
Republic of Korea
Daegu Catholic University Medical Center
RECRUITING
Daegu
Samsung Medical Center
RECRUITING
Seoul
The Catholic University of Korea, Seoul St. Mary's Hospital
RECRUITING
Seoul
Contact Information
Primary
SungJa Cho
sungja_cho@neudive.com
+82-2-6959-9933
Time Frame
Start Date: 2025-10-16
Estimated Completion Date: 2026-08
Participants
Target number of participants: 48
Treatments
Experimental: The experimental group (immediate intervention)
NDTx-02 + TAU for the first 6 weeks (stage 1), followed by TAU only for the following 6 weeks (stage 2).
Other: The waitlist control group (delayed intervention)
TAU only during the first 6 weeks (stage 1), followed by NDTx-02 + TAU for the following 6 weeks (stage 2).
Sponsors
Leads: Neudive Inc.

This content was sourced from clinicaltrials.gov