Autism Spectrum Disorder Clinical Trials

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Fecal Microbiota Transplantation for Gastrointestinal, Autistic, Emotion, and Behavior Symptoms of Patients With Autism Spectrum Disorder and Gastrointestinal Problems: a Preliminary Study.

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

This study aims to evaluate the efficacy of fecal microbiota transplantation on the gastrointestinal symptoms, autistic symptoms and emotional behavior symptoms of patients with autism spectrum disorder, and investigate the relations between the brain-gut axis, cytokines and autism spectrum disorder. Fecal microbiota transplantation have the potentials to improve intestinal microbiota composition, regulate immunity, and then improve gastrointestinal symptoms, autistic symptoms, emotional behavior symptoms and sleep of children with autism spectrum disorder. Early intervention at school-age may even benefit development, improve cognition and prognosis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 7
Maximum Age: 30
Healthy Volunteers: t
View:

• Diagnosed by a child psychiatrist in line with DSM-5 Autism Spectrum Disorder

• Combined with gastrointestinal problems, any Gastrointestinal Symptoms Rating Scale score≧3.

• Age is between 7-30.

• Participants who are willing to participate in the study and sign the informed consent.

Locations
Other Locations
Taiwan
Wei-Chih Chin
RECRUITING
Taoyuan
Contact Information
Primary
Wei-Chih Chin
auaug0327@cgmh.org.tw
+886 3 3281200
Time Frame
Start Date: 2024-03-06
Estimated Completion Date: 2027-07-31
Participants
Target number of participants: 60
Treatments
Experimental: Fecal microbiota transplantation
Children with autism spectrum disorder will receive fecal microbiota transplantation after evaluation. After the first intervention, the second transplantation will be arranged 6 months later.
Sponsors
Leads: Chang Gung Memorial Hospital

This content was sourced from clinicaltrials.gov