Magnetic Resonance Imaging of Hypoxia for Radiation Treatment Guidance in Glioblastoma Multiforme (MANGO)
Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY
This study is designed to evaluate the role of Oxygen Enhanced (OE) Magnetic resonance imaging (MRI) and Blood Oxygenation Level Dependent (BOLD) MRI in detecting regions of hypoxic tumour and to evaluate their use as imaging methods to selectively deliver targeted radiotherapy to regions of aggressive disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Suspected high-grade glioma (HGG) / glioblastoma multiforme (WHO grade IV) at initial radiological examination
• Eastern Cooperative Oncology Group (ECOG) performance status score of 0-2
• Available for scanning on two separate days
Locations
Other Locations
Australia
North Shore Private Hospital
NOT_YET_RECRUITING
St Leonards
Royal North Shore Hospital
RECRUITING
St Leonards
Contact Information
Primary
Shona Silvester
shona.silvester@sydney.edu.au
+61286271185
Backup
David Waddington
david.waddington@sydney.edu.au
Time Frame
Start Date: 2024-08-14
Estimated Completion Date: 2026-12
Participants
Target number of participants: 20
Related Therapeutic Areas
Sponsors
Collaborators: The Brain Cancer Group
Leads: University of Sydney