Investigating the Feasibility, Efficacy, and Renormalization of Pain-Regulation Brain Circuits Underlying At-Home Transcutaneous Auricular Neuromodulation (tAN) for Managing Chronic Post-Stroke Pain
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age 18-80
• Have the capacity and ability to provide one's own consent in English and sign the informed consent document.
• Ischemic or hemorrhagic stroke that occurred at least 6 months prior
Locations
United States
South Carolina
30 Bee Street
RECRUITING
Charleston
Medical University of South Carolia
NOT_YET_RECRUITING
Charleston
Contact Information
Primary
Institutional RBFHR Recruitment Contact
suttonf@musc.edu
843-792-9502
Time Frame
Start Date: 2026-01-08
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 24
Treatments
Experimental: 2 Weeks Sham tAN followed by 2 Weeks Active tAN
Participants will be randomized to receive 2 weeks of at-home, self-administered sham Transcutaneous Auricular Neurostimulation (tAN), followed by 2 weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN).
Experimental: Four Weeks of Active Transcutaneous Auricular Neurostimulation
Participants will be randomized to receive 2 weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN), followed by 2 additional weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN).
Related Therapeutic Areas
Sponsors
Leads: Medical University of South Carolina