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The Effect of Lipedema on Knee Osteoarthritis: A Cross-Sectional Analysis of Clinical Symptoms and Ultrasonographic Findings

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context. Although the relationship between obesity and osteoarthritis has been extensively studied in the literature, the effect of specific adipose tissue pathologies, such as lipedema, on osteoarthritis has not been sufficiently investigated. This study aims to demonstrate the independent effect of lipedema on osteoarthritis, evaluate clinical and ultrasonographic parameters together, and contribute to early diagnosis and targeted rehabilitation strategies.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 30
Maximum Age: 65
Healthy Volunteers: f
View:

⁃ All participants (Group 1 + Group 2)

• Women aged 30-65

• With a clinical and radiological diagnosis of knee osteoarthritis

• Who agreed to participate in the study

⁃ Group 1 (knee osteoarthritis with lipedema):

• Patients who meet the Wold criteria for a clinical diagnosis of lipedema

• An increase in subcutaneous fat thickness confirmed by ultrasound

⁃ Group 2 (knee osteoarthritis without lipedema):

• No diagnosis of lipedema

• Exclusion of lymphedema and venous diseases

Locations
Other Locations
Turkey
Izmir Democracy University
NOT_YET_RECRUITING
Izmir
Izmir Democracy University
RECRUITING
Izmir
Contact Information
Primary
Kadir Songür, Assoc. Prof.
kadir.93@gmail.com
+905054529231
Time Frame
Start Date: 2026-07-07
Estimated Completion Date: 2027-08-15
Participants
Target number of participants: 76
Treatments
Group 1
Knee osteoarthritis with lipedema
Group 2
Knee osteoarthritis without lipedema
Sponsors
Leads: Izmir Democracy University

This content was sourced from clinicaltrials.gov