Karen L. Simon
Advanced in Colitis

Dr. Karen L. Simon

Gastroenterology
CommonSpirit Health
Ventura County Gastroenterology Group
4005 Mission Oaks Blvd, Ste A, 
Camarillo, CA 
Accepting New Patients
Offers Telehealth

Advanced in Colitis
CommonSpirit Health
Ventura County Gastroenterology Group
4005 Mission Oaks Blvd, Ste A, 
Camarillo, CA 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Dr. Karen Simon received her B.A. from Stanford University in 1996. She then attended Northwestern University for medical school. She completed her residency at Cedars-Sinai Medical Center in 2004 and her fellowship at UCLA and Cedars in 2008.Dr. Simon has proudly been serving patients in Ventura County since 2008 and is very involved in field research. Dr. Simon is also a speaker for Exact Sciences on behalf of Cologuard and is actively associated in research studies. She is a part of the Takeda Chloride Channel Council and a speaker for Amitiza, as well.She enjoys educating the doctors and the community as a lecturer on topics such as colorectal cancer screening at St. John's Hospital, where she is also a part of the Ethics Committee.Dr. Simon aims specifically to work with patients to discover the problem and develop a treatment strategy. She has a particular interest in Celiac Disease, Inflammatory Bowel Disease (IBD), and a passion for improving colorectal cancer detection.She is dedicated to developing a relationship with patients by utilizing education and mutual information sharing.

Dr. Simon is rated as an Advanced provider by MediFind in the treatment of Colitis. Her top areas of expertise are Gastroesophageal Reflux Disease (GERD), Familial Adenomatous Polyposis, Painful Swallowing, Endoscopy, and Colonoscopy.

Her clinical research consists of co-authoring 4 peer reviewed articles and participating in 10 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, she has participated in 2 clinical trials in the study of Colitis.

Graduate Institution
Northwestern University Medical Center
Specialties
Gastroenterology
Licenses
Internal Medicine in CA
Board Certifications
Internal Medicine (Sub: Gastroenterology)
Fellowships
Cedars-Sinai Medical Center
Hospital Affiliations
St Johns Regional Medical Center
Languages Spoken
English
Gender
Female

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
Alignment Health Plan
  • MEDICARE MAPD
  • MEDICARE SNP
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
Anthem BCBS
  • EPO
  • HMO
  • POS
  • PPO
Blue Cross Blue Shield
  • EPO
  • HMO
  • POS
  • PPO
Blue Shield of California
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE-MEDICAID PLAN
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
Health Care Services Corporation
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • OTHER COMMERCIAL
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Health Net

Accepted plan types not found. Please verify directly with the provider.

Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
Kaiser Permanente
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • OTHER MEDICARE
  • POS
  • PPO
Managed Medicaid
  • OTHER MANAGED MEDICAID
Medicaid
  • OTHER MEDICAID
  • STATE MEDICAID
Medicare
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE PART D
SCAN Health Plan
  • INSURANCE PLAN
  • MEDICARE MAPD
UnitedHealthcare
  • EPO
  • HMO
  • POS
  • PPO
Wellcare
  • EPO
  • HMO
  • INSURANCE PLAN
  • MANAGED MEDICAID PLAN
  • MEDICARE MAPD
  • MEDICARE PDP
  • MEDICARE SNP
  • MEDICARE-MEDICAID PLAN
  • OTHER MEDICARE
  • OTHER MEDICARE PART D
View 11 Less Insurance Carriers -

Locations

Ventura County Gastroenterology Group
4005 Mission Oaks Blvd, Ste A, Camarillo, CA 93012
Call: 805-484-7921

Additional Areas of Focus

Dr. Simon has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Non-Alcoholic Fatty Liver Disease
Nonalcoholic Steatohepatitis (NASH)

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


10 Clinical Trials

A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Maintenance Study of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 2)
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Maintenance Study of Mirikizumab in Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 2)
Enrollment Status: Completed
Publish Date: October 14, 2025
Intervention Type: Drug
Study Drug: Mirikizumab
Study Phase: Phase 3
Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode
Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode
Enrollment Status: Completed
Publish Date: August 11, 2025
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Induction Study of Mirikizumab in Conventional-Failed and Biologic-Failed Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)
A Phase 3, Multicenter, Randomized, Double-Blind, Parallel, Placebo-Controlled Induction Study of Mirikizumab in Conventional-Failed and Biologic-Failed Patients With Moderately to Severely Active Ulcerative Colitis (LUCENT 1)
Enrollment Status: Completed
Publish Date: May 31, 2025
Intervention Type: Drug
Study Drug: Mirikizumab
Study Phase: Phase 3
Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C
Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C
Enrollment Status: Completed
Publish Date: September 28, 2023
Intervention Type: Other
Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening BLUE-C
Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening BLUE-C
Enrollment Status: Completed
Publish Date: September 01, 2023
Intervention Type: Procedure, Diagnostic test
A Phase 2, Multicenter, Randomized, Parallel-Arm, Placebo-Controlled Study of LY3074828 in Subjects With Active Crohn's Disease (SERENITY)
A Phase 2, Multicenter, Randomized, Parallel-Arm, Placebo-Controlled Study of LY3074828 in Subjects With Active Crohn's Disease (SERENITY)
Enrollment Status: Completed
Publish Date: August 30, 2022
Intervention Type: Drug
Study Drug: Mirikizumab
Study Phase: Phase 2
Specimen Collection Study for Cancer
Specimen Collection Study for Cancer
Enrollment Status: Completed
Publish Date: March 02, 2022
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
Enrollment Status: Completed
Publish Date: June 04, 2021
Intervention Type: Diagnostic test, Procedure
Blood Collection Sub-Study of Exact Sciences Protocol 2018-10: An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
Blood Collection Sub-Study of Exact Sciences Protocol 2018-10: An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
Enrollment Status: Completed
Publish Date: May 17, 2021
Intervention Type: Other
2017-01: Blood Sample Collection to Evaluate Biomarkers for Hepatocellular Carcinoma
2017-01: Blood Sample Collection to Evaluate Biomarkers for Hepatocellular Carcinoma
Enrollment Status: Completed
Publish Date: August 06, 2020
Intervention Type: Other
View 9 Less Clinical Trials

4 Total Publications

Prevention of recurrent Clostridioides difficile infection by fecal microbiota, live-jslm (REBYOTA®) administered via colonoscopy: 6-month data from the single-arm phase IIIb CDI-SCOPE trial.
Prevention of recurrent Clostridioides difficile infection by fecal microbiota, live-jslm (REBYOTA®) administered via colonoscopy: 6-month data from the single-arm phase IIIb CDI-SCOPE trial.
Journal: Therapeutic advances in gastroenterology
Published: October 10, 2025
View All 4 Publications
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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Simon's expertise for a condition
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      • Advanced
      • Alcoholic Cirrhosis
        Dr. Simon is
        Advanced
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      • Bacterial Gastroenteritis
        Dr. Simon is
        Advanced
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      • Chronic Erosive Gastritis
        Dr. Simon is
        Advanced
        . Learn about Chronic Erosive Gastritis.
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      • Colitis
        Dr. Simon is
        Advanced
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      • Colonoscopy
        Dr. Simon is
        Advanced
        . Learn about Colonoscopy.
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      • Diarrhea
        Dr. Simon is
        Advanced
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      View All 21 Advanced Conditions
      • Experienced
      • Anemia
        Dr. Simon is
        Experienced
        . Learn about Anemia.
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      • Angiodysplasia of the Colon
        Dr. Simon is
        Experienced
        . Learn about Angiodysplasia of the Colon.
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      • Ascites
        Dr. Simon is
        Experienced
        . Learn about Ascites.
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      • Attenuated Familial Adenomatous Polyposis
        Dr. Simon is
        Experienced
        . Learn about Attenuated Familial Adenomatous Polyposis.
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      • Banti's Syndrome
        Dr. Simon is
        Experienced
        . Learn about Banti's Syndrome.
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      • Benign Esophageal Stricture
        Dr. Simon is
        Experienced
        . Learn about Benign Esophageal Stricture.
        See more Benign Esophageal Stricture experts
      View All 48 Experienced Conditions
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