Evaluation of the Usefulness of Echocardiography in Patients With Staphylococcus Aureus Bacteremia at Low Risk of Infective Endocarditis (ET-AUREUS Study).

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this prospective interventionist cohort study is to assess the prevalence of infective endocarditis in patients with Staphylococcus aureus bacteremia at low risk of this complication. The main questions it aims to answer are: * Determine whether the risk of infective endocarditis in patients with Staphylococcus aureus bacteriemia identified as low-risk, using the VIRSTA score, is low enough to safely omit transthoracic or transesophageal echocardiography. * Determine whether the risk of infective endocarditis in patients with Staphylococcus aureus bacteriemia in patients with no identifiable risk factor is low enough to safely omit transthoracic or transesophageal echocardiography. * Calculate a cost-benefit estimate of omitting echocardiographic testing in patients identified as low-risk by means of the above methods. Participants will undergo mandatory transthoracic and transesophageal echocardiography during the first 2 weeks from Staphylococcus aureus bacteremia onset.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients with Staphylococcus aureus bacteremia

Locations
Other Locations
Spain
University Hospital Puerta de Hierro
RECRUITING
Majadahonda
Time Frame
Start Date: 2023-09-04
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 470
Treatments
Other: Echocardiography intervention
Patients will undergo mandatory transthoracic echocardiography during assessment of Staphylococcus aureus bacteremia.~Later, they will also undergo mandatory transesophageal echocardiography.~Both test will be performed during the first 14 days from bacteremia onset.
Sponsors
Leads: Puerta de Hierro University Hospital
Collaborators: Hospital Universitario La Paz, Hospitales Universitarios Virgen del Rocío, Hospital Santa Cruz de Tenerife, Hospital de Donosti, Hospital Mutua de Terrassa, Hospital de Alava, Hospital de Basurto, Hospital Rafael Mendez, Hospital Universitario Virgen Macarena, Hospital Universitario Virgen de la Arrixaca, Gregorio Marañón Hospital, University Hospital Virgen de las Nieves, Hospital Infanta Sofia

This content was sourced from clinicaltrials.gov