TRUE-GRIT: Reducing Cognitive Impairment in Glioma with Repetitive Transcranial Magnetic Stimulation and Cognitive Strategy Training
The TRUE-GRIT study will assess the feasibility of a study protocol investigating the efficacy of a combination therapy consisting of cognitive strategy training (CST) and repetitive transcranial magnetic stimulation (rTMS) to reduce cognitive impairment in adult glioma patients. This study is part of the GRIP-project, a project aimed at investigating interventions for improving quality of life in brain tumor patients.
• ≥ 18 years of age
• Histological diagnosis of diffuse glioma (WHO grade 2,3, or 4)
• Subjective cognitive impairment, defined as CFQ-score ≥ 44
• Being able to give informed consent and undergo treatment and measurements based on researchers insight
• Stable disease, i.e. no oncological treatment for ≤ 2 months prior to inclusion; no radiological progression on the most recent MRI, not older than 6 months, and no clinical progression at inclusion
• Stable dosage (for at least 8 weeks) of anti-epileptic medication