Intensity-Modulated Stereotactic Radiotherapy as an Upfront Scalp-Sparing Intervention for the Treatment of Newly Diagnosed Grade II-IV Gliomas

Who is this study for? Patients with Glioma, Glioblastoma
What treatments are being studied? Intensity-Modulated Radiation Therapy+Quality-of-Life
Status: Recruiting
Location: See location...
Intervention Type: Other, Radiation
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This phase II trial studies how well intensity-modulated stereotactic radiation therapy works in treating patients with grade II-IV glioma. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients must have histologically confirmed low or high grade glioma (grade II-IV)

• Karnofsky performance status (KPS) \>= 60

• Patients must have recovered from the effects of surgery; there must be a minimum of 21 days from the day of surgery to the day of protocol treatment

• Estimated survival \>= 3 months

• Labs considered acceptable per standard of care

• Patient must sign a study specific informed consent form

• Radiation treatment must begin \>= 3 weeks and =\< 8 weeks after surgery

Locations
United States
Pennsylvania
Sidney Kimmel Cancer Center at Thomas Jefferson University
RECRUITING
Philadelphia
Contact Information
Primary
Wenyin Shi, MD
wenyin.shi@jefferson.edu
(215) 955-6702
Time Frame
Start Date: 2017-07-17
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 125
Treatments
Experimental: Treatment (IM-SRT)
Patients undergo intensity-modulated (IM)-stereotactic radiotherapy (SRT) daily over 6 weeks.
Authors
David Andrews
Sponsors
Leads: Sidney Kimmel Cancer Center at Thomas Jefferson University

This content was sourced from clinicaltrials.gov

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