Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Adolescents and young adults with sickle cell disease (SCD) face challenges managing their illness and maintaining their well-being. This study proposes to test the feasibility and acceptability of a resilience-promoting intervention through a Collaborative Care Model. The primary goal is to determine with the resilience intervention (PRISM) is feasible and acceptable for adolescents and young adults with SCD. Exploratory outcomes include whether this intervention improves depression, anxiety, and pain interference.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 25
Healthy Volunteers: f
View:

• Aged ≥ 12 and ≤ 25 years of age at baseline

• Diagnosed with Sickle Cell Disease (HbSS, HbSC, HbS-Beta Thalassemia, and other related hemoglobinopathies)

• Receiving Medical Care at the DFCI/BCH Blood Disorders Center.

• Scored \> 9 on Patient Health Questionnaire 9-item (PHQ-9) or Generalized Anxiety Disorder (GAD)

• Able to speak English or Spanish language (for PRISM sessions)

• Able to read English or Spanish language (for completion of surveys)

• Cognitively able to participate in PRISM sessions and complete written questionnaires and surveys, as judged by the site investigator

• Willing and able to adhere to the study visit schedule and other protocol requirements

Locations
United States
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Contact Information
Primary
Abby Rosenberg, MD
abbyr_rosenberg@dfci.harvard.edu
617.632.5286
Time Frame
Start Date: 2025-10-23
Estimated Completion Date: 2030-09
Participants
Target number of participants: 25
Treatments
Experimental: CoCM+PRISM
Collaborative Care Model (CoCM) includes a care manager, a defined population of patents/registry for tracking inclusion and progress, validated patient-reported outcome measures, and weekly inter-professional team meetings. This arm includes the use of an inter professional team to triage, plan and deliver care. the PRISM intervention, a brief, skills-based program targeting 4 resilience resources, will be delivered 1:1 as part of this treatment arm.
Sponsors
Collaborators: National Institutes of Health (NIH)
Leads: Boston Children's Hospital

This content was sourced from clinicaltrials.gov