Study of the Role of Genetic Modifiers in Hemoglobinopathies
Status: Recruiting
Location: See all (26) locations...
Intervention Type: Genetic
Study Type: Observational
SUMMARY
This study will investigate the role of genetic modifiers in hemoglobinopathies through a large-scale, multi-ethnic genome-wide association study (GWAS).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 2
Healthy Volunteers: f
View:
• Clinical diagnosis of an inherited hemoglobinopathy, including sickle cell disease (SCD), β-thalassemia, and α-thalassemia; all genotypes will be considered.
• Age ≥ 2 years old at the time of the collection of the phenotypic data.
• There will be no limits on study participants in terms of gender, ethnicity, morbidities.
Locations
United States
Massachusetts
Boston Children's Hospital
RECRUITING
Boston
Other Locations
Angola
Lucrecia Paím Maternity
RECRUITING
Luanda
Argentina
University of Buenos Aires
NOT_YET_RECRUITING
Buenos Aires
Belgium
University Hospitals Leuven
NOT_YET_RECRUITING
Leuven
Brunei Darussalam
Universiti Brunei Darussalam
NOT_YET_RECRUITING
Brunei
Cyprus
Larnaca General Hospital
RECRUITING
Larnaca
Limassol General Hospital
RECRUITING
Limassol
Archbishop Makarios III Hospital
RECRUITING
Nicosia
Paphos General Hospital
RECRUITING
Paphos
Democratic Republic of the Congo
Centre Hospitalier Monkole
RECRUITING
Kinshasa
Denmark
Rigshospitalet
RECRUITING
Copenhagen
Greece
Hippokrateio Hospital of Athens
RECRUITING
Athens
Laiko General Hospital
RECRUITING
Athens
National and Kapodistrian University of Athens
NOT_YET_RECRUITING
Athens
General Hospital of Larissa
RECRUITING
Larissa
Israel
Emek Medical Centre
NOT_YET_RECRUITING
Afula
Italy
University of Turin
NOT_YET_RECRUITING
Turin
Malaysia
Ampang Hospital
RECRUITING
Ampang
Universiti Kebangsaan Malaysia
RECRUITING
Bangi
Universiti Sains Malaysia
RECRUITING
Kota Bharu
Nigeria
University of Abuja
RECRUITING
Abuja
Kaduna State University
RECRUITING
Kaduna
Ahmadu Bello University
RECRUITING
Zaria
Pakistan
University of Lahore
NOT_YET_RECRUITING
Lahore
Portugal
Centro Hospitalar e Universitário de Coimbra
NOT_YET_RECRUITING
Coimbra
Spain
Hospital Clínico San Carlos
NOT_YET_RECRUITING
Madrid
Contact Information
Primary
Petros Kountouris, PhD
admin@inherentnetwork.org
22392623
Time Frame
Start Date: 2022-10-01
Estimated Completion Date: 2027-09-30
Participants
Target number of participants: 30000
Treatments
Cohort
Individuals with hemoglobinopathies
Related Therapeutic Areas
Sponsors
Leads: Cyprus Institute of Neurology and Genetics