Investigating Improvement of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in Perimenopausal Women
Status: Recruiting
Location: See location...
Intervention Type: Biological, Other
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 40
Maximum Age: 50
Healthy Volunteers: t
View:
• Women ≥40 years of age, presenting with cycle irregularities while fulfilling at least one of the respective two criteria: more than seven days difference in menstrual cycle duration between two consecutive cycles OR, presence of a menstrual cycle duration over sixty days and progressive elevation of FSH levels.
• Discontinuation of any complementary/adjuvant treatment including hormone replacement, acupuncture, and botanotherapy, for at least three months prior to recruitment.
• Willing to comply with study requirements
Locations
Other Locations
Greece
Genesis AC
RECRUITING
Athens
Contact Information
Primary
Mara Simopoulou, PhD
marasimopoulou@hotmail.com
+306979234100
Backup
Agni Pantou, MD, PhD Candidate
agni.pantou@genesisathens.gr
Time Frame
Start Date: 2019-06-13
Estimated Completion Date: 2025-07-30
Participants
Target number of participants: 100
Treatments
Experimental: Participants receiving PRP treatment
Perimenopausal women, 40-50 years of age, treated with autologous PRP intra ovarian infusion.
Placebo_comparator: Participants receiving Platelet Free Plasma (PFP)
Perimenopausal women, 40-50 years of age, treated with autologous PRP intra ovarian infusion.
Related Therapeutic Areas
Sponsors
Collaborators: National and Kapodistrian University of Athens
Leads: Genesis Athens Clinic