Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This is a single-center study that aims to better understand how diet and sex affect the risk of kidney stones in people who have had gastric bypass surgery. Subjects will be asked to follow a special (clinic-provided) diet for six days and come to a research clinic for 3 study visits.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 130
Healthy Volunteers: f
View:
• Participants without history of stone disease, family history of stone disease
• Participants pre-bariatric surgery who are approved and planned for surgery in the Bariatric Surgery Center at University of Chicago Medicine.
Locations
United States
Illinois
University of Chicago Medical Center
RECRUITING
Chicago
Contact Information
Primary
Megan Prochaska
mprocha2@medicine.bsd.uchicago.edu
(773) 702-1000
Backup
Prochaska Megan, MD
mprocha2@medicine.bsd.uchicago.edu
(773) 702-1000
Time Frame
Start Date: 2020-11-01
Estimated Completion Date: 2026-04-01
Participants
Target number of participants: 28
Treatments
Experimental: Roux-en-y gastric bypass subjects
Inclusion Criteria: Age 18-70. Participants pre-Roux-en-y gastric bypass (RYGB) who are approved and planned for Roux-en-y gastric bypass surgery in the Bariatric Surgery Center at the UCM.~Exclusion Criteria: Patients with primary kidney diseases, kidney stone disease, or kidney impairment (eGFR \< 90). Patients with known bladder voiding problems.~Participants will complete a diet record and a 24-hour urine collection both before and after surgery.~Participants will consume a 3 day fixed diet and present to the clinical research center for timed blood and urine draws. They will do this before and twice after (1 month and 1 year) surgery.
Experimental: Sleeve gastrectomy subjects
Inclusion Criteria: Age 18-70. Participants pre-sleeve gastrectomy who are approved and sleeve gastrectomy in the Bariatric Surgery Center at the UCM.~Exclusion Criteria: Patients with primary kidney diseases, kidney stone disease, or kidney impairment (eGFR \< 90). Patients with known bladder voiding problems.~Participants will complete a diet record and a 24-hour urine collection both before and after surgery.~Participants will consume a 3 day fixed diet and present to the clinical research center for timed blood and urine draws. They will do this before and twice after (1 month and 1 year) surgery.
Related Therapeutic Areas
Sponsors
Leads: University of Chicago