Experienced in Metastatic Brain Tumor

Dr. Mark C. Markowski

Oncology
Johns Hopkins Medicine
Sibley Memorial Hospital
5255 Loughboro Road Northwest, Building B, Building B, 
Washington, DC 
Offers Telehealth
17 Years of Experience

Experienced in Metastatic Brain Tumor
Johns Hopkins Medicine
Sibley Memorial Hospital
5255 Loughboro Road Northwest, Building B, Building B, 
Washington, DC 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Dr. Mark Markowski is a medical oncologist at the Kimmel Cancer Center at Sibley Memorial Hospital, as well as an Associate Professor in the Department of Oncology at Johns Hopkins University School of Medicine. Dr. Markowski participates in multidisciplinary clinics at Sibley and The Johns Hopkins Hospital, and sees patients in the genitourinary clinics of both hospitals. Dr. Markowski treats numerous types of cancers, with a specialty in prostate and kidney cancers. Dr. Markowski earned his medical degree and Ph.D. in tumor biology at Georgetown University School of Medicine. He completed a residency in internal medicine at Columbia University, followed by a medical oncology fellowship at Johns Hopkins Hospital. Dr. Markowski previously served as a research associate at the Lombardi Comprehensive Cancer Center at Georgetown University. His research interests focus on early phase drug development for prostate cancer, as well a non-castrating therapies for patients with metastatic disease. Dr. Markowski is currently conducting research with funding from a Department of Defense Prostate Cancer Research Program Award and a Challenge Award from the Prostate Cancer Foundation, which focuses on new treatment strategies for prostate cancer patients.

Dr. Markowski is rated as an Experienced provider by MediFind in the treatment of Metastatic Brain Tumor. His top areas of expertise are Prostate Cancer, Renal Cell Carcinoma (RCC), Wilms Tumor, Hormone Replacement Therapy (HRT), and Prostatectomy.

His clinical research consists of co-authoring 74 peer reviewed articles and participating in 8 clinical trials. MediFind looks at clinical research from the past 15 years.

Graduate Institution
Georgetown University School Of Medicine, PhD, 2009, 2009
Residency
New York-Presbyterian University Hospital of Columbia and Cornell, Internal Medicine, 2012
Specialties
Oncology
Licenses
Internal Medicine in MD
Fellowships
Johns Hopkins University School of Medicine, Medical Oncology, 2016
Hospital Affiliations
Sibley Memorial Hospital
The Johns Hopkins Hospital
Languages Spoken
English
Gender
Male

Insurance

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
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Health Care Services Corporation
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  • OTHER MEDICARE
  • OTHER MEDICARE PART D
  • PPO
Humana
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Johns Hopkins Healthcare
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Locations

Sibley Memorial Hospital
5255 Loughboro Road Northwest, Building B, Building B, Washington, DC 20016
Call: 202-660-6500

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


8 Clinical Trials

Nivolumab as a Non-Castrating Therapy for MMR-deficient and CDK12- Altered Prostate Cancer With PSA Recurrence After Local Therapy
Nivolumab as a Non-Castrating Therapy for MMR-deficient and CDK12- Altered Prostate Cancer With PSA Recurrence After Local Therapy
Enrollment Status: Completed
Publish Date: October 23, 2025
Intervention Type: Drug
Study Drug: Nivolumab
Study Phase: Phase 2
A Phase II Randomized Trial of RAdium-223 and SABR Versus SABR for oligomEtastatic Prostate caNcerS (RAVENS)
A Phase II Randomized Trial of RAdium-223 and SABR Versus SABR for oligomEtastatic Prostate caNcerS (RAVENS)
Enrollment Status: Active_not_recruiting
Publish Date: November 04, 2024
Intervention Type: Drug, Radiation
Study Drug: Radium-223
Study Phase: Phase 2
Phase II Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations (TRIUMPH)
Phase II Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutations (TRIUMPH)
Enrollment Status: Completed
Publish Date: October 16, 2024
Intervention Type: Drug
Study Drug: Rucaparib
Study Phase: Phase 2
COMbination of Bipolar Androgen Therapy and Nivolumab in Patients With Metastatic Castration-Resistant Prostate Cancer
COMbination of Bipolar Androgen Therapy and Nivolumab in Patients With Metastatic Castration-Resistant Prostate Cancer
Enrollment Status: Completed
Publish Date: February 20, 2024
Intervention Type: Drug
Study Drugs: Testosterone cypionate, Nivolumab
Study Phase: Phase 2
A Phase 1, Open-label Study in Two Parts, Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Activity of CCW702 in Patients With Metastatic, Castration Resistant Prostate Adenocarcinoma
A Phase 1, Open-label Study in Two Parts, Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Activity of CCW702 in Patients With Metastatic, Castration Resistant Prostate Adenocarcinoma
Enrollment Status: Terminated
Publish Date: May 12, 2023
Intervention Type: Drug
Study Drug: CCW702 Immunotherapy
Study Phase: Phase 1
A Phase 2 Study of Apalutamide in Active Surveillance Patients
A Phase 2 Study of Apalutamide in Active Surveillance Patients
Enrollment Status: Terminated
Publish Date: February 09, 2023
Intervention Type: Other, Drug
Study Drug: Apalutamide
Study Phase: Phase 2
A Phase IB Open-label, Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK525762 in Combination With Androgen Deprivation Therapy and Other Agents in Subjects With Castrate-resistant Prostate Cancer (CRPC)
A Phase IB Open-label, Dose Escalation and Expansion Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of GSK525762 in Combination With Androgen Deprivation Therapy and Other Agents in Subjects With Castrate-resistant Prostate Cancer (CRPC)
Enrollment Status: Terminated
Publish Date: August 10, 2022
Intervention Type: Drug
Study Drugs: GSK525762, Abiraterone, Enzalutamide, Prednisone
Study Phase: Phase 1
Study of 18F-DCFPyL PET/CT, for Detection of Radiological Progression in Patients With Metastatic (M+) and Non-metastatic (M0) Castration Resistant Prostate Cancer Receiving Standard Androgen Receptor Targeted Treatment
Study of 18F-DCFPyL PET/CT, for Detection of Radiological Progression in Patients With Metastatic (M+) and Non-metastatic (M0) Castration Resistant Prostate Cancer Receiving Standard Androgen Receptor Targeted Treatment
Enrollment Status: Withdrawn
Publish Date: December 15, 2021
Intervention Type: Drug
Study Drug: 18F-DCFPyL Injection
Study Phase: Phase 2/Phase 3
View 7 Less Clinical Trials

74 Total Publications

National Cancer Institute's Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations.
National Cancer Institute's Working Group on Biochemically Recurrent Prostate Cancer: Clinical Trial Design Considerations.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Published: October 23, 2025
View All 74 Publications
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Dr. Matthias Holdhoff is a medical oncologist and co-director of the Brain Cancer Disease Group at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. He is a professor of oncology, neurology and neurological surgery at Johns Hopkins University School of Medicine. Dr. Holdhoff’s expertise is in primary brain cancers and central nervous system lymphomas. He earned his medical degree from Freie Universität Berlin, received his doctorate degree at Charité University Medicine Berlin. Dr. Holdhoff completed residency training in internal medicine at Johns Hopkins Bayview Medical Center, followed by a fellowship in medical oncology at Johns Hopkins Hospital with research training at the Ludwig Center for Cancer Genetics and Therapeutics (Kinzler-Vogelstein lab). As a clinical investigator in neuro-oncology, his research is focused on novel trials and translational biomarker studies in malignant gliomas and primary central nervous system lymphomas. He has led and contributed to numerous clinical trials, publications and presentations. Dr. Holdhoff serves as the director of the solid tumor inpatient service at the Sidney Kimmel Comprehensive Cancer Center. He is passionately involved in mentoring and teaching of fellows, residents and students. He is the director of the UCNS-certified neuro-oncology fellowship program at Johns Hopkins, and he is a teaching attending physician for the Osler internal medicine residency program. Dr. Holdhoff is rated as an Elite provider by MediFind in the treatment of Metastatic Brain Tumor. His top areas of expertise are Glioma, Glioblastoma, Astrocytoma, and Brain Tumor.

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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

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  • Elite
  • Hormone Replacement Therapy (HRT)
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    Elite
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  • Prostate Cancer
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  • Distinguished
  • Chromophobe Renal Cell Carcinoma
    Dr. Markowski is
    Distinguished
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  • Clear Cell Sarcoma
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  • Familial Prostate Cancer
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  • Familial Wilms Tumor 2
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  • Renal Cell Carcinoma (RCC)
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  • Wilms Tumor
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  • Advanced
  • Adult Soft Tissue Sarcoma
    Dr. Markowski is
    Advanced
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  • NUT Carcinoma
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  • Prostatectomy
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  • Experienced
  • Alveolar Soft Part Sarcoma
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    Experienced
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  • Bladder Cancer
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  • Bone Tumor
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  • Brain Tumor
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  • Metastatic Brain Tumor
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  • Muscle Invasive Bladder Cancer
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