International Prospective Registry on Local Treatment Approaches in Myxoid Liposarcomas
Status: Recruiting
Location: See location...
Intervention Type: Radiation, Procedure
Study Type: Observational
SUMMARY
To prospectively study commonly used local treatment approaches in Myxoid Liposarcoma (MLS)
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Age \> 18 years
• Biopsy proven MLS, including the reciprocal chromosomal translocation t(12;16)(q13;p11)
• ECOG PS 0-2
• Written informed consent to share coded information in this international Registry
Locations
Other Locations
Netherlands
The Netherlands Cancer Institute
RECRUITING
Amsterdam
Contact Information
Primary
Rick Haas, MD/PhD
r.haas@nki.nl
+31 20 512 9111
Backup
Jules Lansu, MD/PhD
j.lansu@nki.nl
+31 20 512 9111
Time Frame
Start Date: 2021-01-18
Estimated Completion Date: 2031-01
Participants
Target number of participants: 300
Treatments
Cohort A
MLS patients managed by surgery only
Cohort B
MLS patients receiving preoperative RT to a dose of 36 Gy (equivalent) followed by surgery
Cohort C
MLS patients receiving preoperative RT to a dose of 50 Gy (equivalent) followed by surgery
Cohort D
MLS patients receiving surgery followed by postoperative RT to a dose of 50-66 Gy (equivalent)
Cohort E
MLS patients with oligometastatic and/or oligoprogressive disease receiving definitive RT to a dose of 36Gy (equivalent)
Related Therapeutic Areas
Sponsors
Collaborators: Mayo Clinic, University Medical Center Groningen, Universitäts-Frauenklinik Graz, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, National Cancer Center, Japan, Radboud University Medical Center, Princess Margaret Hospital, Canada, MOUNT SINAI HOSPITAL, Australia and New Zealand Sarcoma Association, M.D. Anderson Cancer Center, Leiden University Medical Center, Aarhus University Hospital, Institut Curie, Institute for Cancer Research and treatment, Vienna General Hospital, Haukeland University Hospital, University Hospital, Antwerp, University of Sydney, Maastro Clinic, The Netherlands, Universitetssykehus, University Hospital Heidelberg
Leads: The Netherlands Cancer Institute