Single Neuron Population Dynamics in Human Speech Motor Cortex for a Speech Prosthesis
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with their thoughts.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Between 18 and 80 years of age.
• Participants must have a diagnosis of amyotrophic lateral sclerosis (ALS) as verified by a clinical expert in neurologic diseases.
• Participants with a diagnosis of ALS with anarthria, or severe dysarthria with decline in the preceding four months.
• Must be within a three-hour drive of the Study site and geographically stable for at least 15 months after enrollment.
Locations
United States
California
Stanford University School of Medicine
RECRUITING
Stanford
Massachusetts
Massachusetts General Hospital
RECRUITING
Boston
Contact Information
Primary
Leigh R Hochberg, MD, Ph.D
lhochberg@mgh.harvard.edu
617-724-9247
Backup
Jaimie Henderson, MD
henderj@stanford.edu
650-723-5574
Time Frame
Start Date: 2023-10-18
Estimated Completion Date: 2026-12
Participants
Target number of participants: 3
Treatments
Other: BrainGate Neural Interface System
Placement of the BrainGate2 sensor(s) into the speech-related cortex
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Deafness and Other Communication Disorders (NIDCD)
Leads: Leigh R. Hochberg, MD, PhD.