Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thoracic Postherpetic Neuralgia: A Retrospective Cohort Study

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Postherpetic neuralgia (PHN) is a chronic pain syndrome that can be resistant to treatment, leading to physical and social disability, psychological disturbances, and potentially persisting for years . The varicella-zoster virus remains latent in the sensory neurons of individuals who have previously contracted varicella (chickenpox). Reactivation of the latent virus results in herpes zoster (HZ). In most patients, HZ initially presents with dermatomal pain, and within a few days, characteristic dermatomal vesicular eruptions typically develop. These skin lesions usually heal within 2-4 weeks; however, pain may persist even after the resolution of the rash . The pathogenesis of PHN involves increased sensitization of central neurons, decreased function of inhibitory neuronal pathways, inflammation and nerve injury within the peripheral nervous system, and abnormal signal transmission following such damage. PHN represents the most common complication of HZ. It occurs in approximately 9-19% of all patients with HZ. The incidence of PHN increases with advancing age: it affects approximately 2% of individuals younger than 50 years, about 20% of those older than 50 years, and nearly 35% of those older than 80 years . Various treatment modalities, including pharmacologic agents and interventional procedures, are available for the management of PHN-related pain.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients over 18 years of age

• \- who underwent a single-session ultrasound (US)-guided serratus posterior superior intercostal plane block (SPSIPB) in the thoracic region (T1-T10 dermatomes) for PHN between June 2023 and February 2025 were evaluated. -SPSIPB was performed in patients whose complaints persisted despite existing medical treatments.

Locations
Other Locations
Turkey
İKanuni Sultan Süleyman Training and Research Hospital
RECRUITING
Küçükçekmece
Contact Information
Primary
halil ibrahim altun, specialist
halilibrahim_altun@yahoo.com
+905072774773
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2025-08-15
Participants
Target number of participants: 34
Treatments
Effectiveness of Ultrasonography-Guided Serratus Posterior Superior Intercostal Plane Block in Thora
Sponsors
Leads: Kanuni Sultan Suleyman Training and Research Hospital

This content was sourced from clinicaltrials.gov