Relationship Between Parameters of Glycemic Control and Irisin Levels in Patients With Diabetes Mellitus Type 2 and Sarcopenic Obesity or Non-sarcopenic Obesity

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity. The main questions it aims to answer are: Is glycemic control worse in diabetic patients with sarcopenic obesity? Are irisin levels higher in patients with non-sarcopenic obesity? Participants will be asked to: * Fill in three questionaries on lifestyle * Perform two physical performance tests The investigators will collect the following data: * Anthropometric measurements * Body composition by bioelectrical impedance analysis. * Results of routine blood analyses * Irisin levels by drawing a vial of blood from the antecubital vein

Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:

• Diabetes mellitus type 2 diagnosed less than 10 years before

• age \>60 years

• BMI (Body Mass Index) \>30 kg/m2

• eGFR (estimated Glomerular Filtration Rate) \>30 ml/min

• On stable antidiabetic therapy for at least 3 months

Locations
Other Locations
Italy
Policlinico di Bari
RECRUITING
Bari
Contact Information
Primary
Francesco Giorgino, MD, PhD
francesco.giorgino@uniba.it
+390805593522
Time Frame
Start Date: 2023-02-01
Estimated Completion Date: 2025-01-31
Participants
Target number of participants: 120
Treatments
Sarcopenic obesity
BMI\>30, bioelectric impedance positive for sarcopenic obesity (FM% \[fat mass percentage\] female \>43%, male \>31% AND SMM/W \[skeletal muscle mass/weight\] female \<28%, male \<37%), any one of the physical performance test positive (5-times chair stand test \>17 s OR handgrip strength test \<35,5 kg for males, \<20 kg for females).
Non-sarcopenic obesity
BMI\>30, bioelectric impedance negative for sarcopenic obesity.
Sponsors
Leads: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari

This content was sourced from clinicaltrials.gov