Theodore Deweese
Distinguished in Prostate Cancer

Dr. Theodore Deweese

Radiation Oncology
Johns Hopkins Medicine
Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Floor-L1 (Lobby Level), Weinberg BLDG, Floor-L1 (Lobby Level), 
Baltimore, MD 

Distinguished in Prostate Cancer
Johns Hopkins Medicine
Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Floor-L1 (Lobby Level), Weinberg BLDG, Floor-L1 (Lobby Level), 
Baltimore, MD 
OverviewInsuranceLocationsClinical ResearchSimilar Doctors

Overview

Theodore DeWeese is The Frances Watt Baker, M.D., and Lenox D. Baker Jr., M.D. Dean of the Medical Faculty and CEO, Johns Hopkins Medicine. Dr. DeWeese is professor of oncology and urology at the Johns Hopkins University School of Medicine. His areas of clinical expertise include prostate cancer, radiation oncology and urological oncology. He and his colleagues focus their research on developing new ways to enhance radiation-induced killing of prostate cancer cells. This includes development of novel, prostate cancer-targeted RNA molecules as well as new ways to modulate androgen receptor signaling. He and his colleagues also developed the first adenoviral gene therapy trial for prostate cancer, using a common cold virus to target cancer cells while leaving normal cells unharmed. Dr. DeWeese earned his M.D. from the University of Colorado Health Sciences Center. He completed his residency at The Johns Hopkins Hospital, serving as chief resident, and performed a laboratory research fellowship at the Johns Hopkins Oncology Center and the James Buchanan Brady Urological Institute. Dr. DeWeese's research interests include prostate cancer, DNA damage, and radiation sensitization. Dr. DeWeese has served on numerous committees and boards including as President and Chair of the Board for the American Society for Radiation Oncology. He also serves on committees for the American Association for Cancer Research and was appointed by the National Academy of Sciences as a scientific counselor for the Radiation Effects Research Foundation in Hiroshima, Japan. He has received numerous awards and honors, including several teaching awards from Johns Hopkins. Make A Gift.

Dr. Deweese is rated as a Distinguished provider by MediFind in the treatment of Prostate Cancer. His top areas of expertise are Prostate Cancer, Familial Prostate Cancer, Bone Tumor, Prostatectomy, and Orchiectomy.

His clinical research consists of co-authoring 144 peer reviewed articles and participating in 9 clinical trials. MediFind looks at clinical research from the past 15 years. In particular, he has co-authored 81 articles and participated in 8 clinical trials in the study of Prostate Cancer.

Residency
Johns Hopkins University School of Medicine, Radiation Oncology, 1994
Specialties
Radiation Oncology
Licenses
Radiology in MD
Board Certifications
American Board Of Radiology
Languages Spoken
English
Gender
Male

Insurance

Accepted insurance can change. Please verify directly with the provider.

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Accepted insurance plans:

Aetna
  • EPO
  • HMO
  • POS
  • PPO
CareFirst
  • HMO
  • POS
  • PPO
Cigna
  • EPO
  • HMO
  • PPO
First Health
  • INSURANCE PLAN
  • MEDICARE PDP
  • PPO
Geisinger
  • HMO
  • POS
  • PPO
Humana
  • HMO
  • INDEMNITY
  • POS
  • PPO
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Locations

Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg BLDG, Floor-L1 (Lobby Level), Weinberg BLDG, Floor-L1 (Lobby Level), Baltimore, MD 21287
Call: 410-502-8000
Other Locations
Sidney Kimmel Comprehensive Cancer Center
401 North Broadway Street, Weinberg Building, Floor-L2, Baltimore, MD 21287
Call: 410-502-8000

Additional Areas of Focus

Dr. Deweese has provided the following conditions as areas of focus. Please note that we may not have enough data to validate their experience in some of these conditions.

Prostate Cancer

Clinical Research

Clinical research consists of overseeing clinical studies of patients undergoing new treatments and therapies, and publishing articles in peer reviewed medical journals. Providers who actively participate in clinical research are generally at the forefront of the fields and aware of the most up-to-date advances in treatments for their patients.


9 Clinical Trials

Multiparametric MRI for Assessing Radiotherapy Treatment Response of Prostate Cancer
Multiparametric MRI for Assessing Radiotherapy Treatment Response of Prostate Cancer
Enrollment Status: Active_not_recruiting
Publish Date: November 28, 2025
Intervention Type: Other
Study Phase: Not Applicable
Phase II Randomized Placebo-Controlled Double-Blind Study of Salvage Radiation Therapy (SRT) Plus Placebo Versus SRT Plus Enzalutamide in Men With High-Risk PSA-Recurrent Prostate Cancer After Radical Prostatectomy
Phase II Randomized Placebo-Controlled Double-Blind Study of Salvage Radiation Therapy (SRT) Plus Placebo Versus SRT Plus Enzalutamide in Men With High-Risk PSA-Recurrent Prostate Cancer After Radical Prostatectomy
Enrollment Status: Completed
Publish Date: October 28, 2025
Intervention Type: Drug, Radiation
Study Drug: Enzalutamide
Study Phase: Phase 2
Randomized Trial Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression
Randomized Trial Assessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Suppression
Enrollment Status: Completed
Publish Date: October 16, 2025
Intervention Type: Other, Drug
Study Drug: Flutamide
Study Phase: Early Phase 1
A Randomized Controlled Trial of ProstAtak® as Adjuvant to Up-front Radiation Therapy For Localized Prostate Cancer
A Randomized Controlled Trial of ProstAtak® as Adjuvant to Up-front Radiation Therapy For Localized Prostate Cancer
Enrollment Status: Active_not_recruiting
Publish Date: July 30, 2025
Intervention Type: Biological
Study Drugs: Aglatimagene besadenovec, Valacyclovir
Study Phase: Phase 3
Non-invasive Detection of Cancer DNA in Blood and Urine
Non-invasive Detection of Cancer DNA in Blood and Urine
Enrollment Status: Active_not_recruiting
Publish Date: July 04, 2025
Intervention Type: Procedure
Evaluation of PSMA-based PET as an Imaging Biomarker of Androgen Receptor Signaling in High-Risk Localized and Locally Advanced Prostate Cancer
Evaluation of PSMA-based PET as an Imaging Biomarker of Androgen Receptor Signaling in High-Risk Localized and Locally Advanced Prostate Cancer
Enrollment Status: Completed
Publish Date: March 19, 2025
Intervention Type: Drug
Study Drug: DCFPyL
Study Phase: Early Phase 1
A Phase II Randomized Trial of RAdium-223 and SABR Versus SABR for oligomEtastatic Prostate caNcerS (RAVENS)
A Phase II Randomized Trial of RAdium-223 and SABR Versus SABR for oligomEtastatic Prostate caNcerS (RAVENS)
Enrollment Status: Active_not_recruiting
Publish Date: November 04, 2024
Intervention Type: Drug, Radiation
Study Drug: Radium-223
Study Phase: Phase 2
Stereotactic Body Radiation Therapy and Short-Term Androgen Ablation for Intermediate-Risk, Localized, Adenocarcinoma of the Prostate
Stereotactic Body Radiation Therapy and Short-Term Androgen Ablation for Intermediate-Risk, Localized, Adenocarcinoma of the Prostate
Enrollment Status: Active_not_recruiting
Publish Date: June 07, 2024
Intervention Type: Drug, Radiation
Study Drug: Androgen deprivation therapy 
Study Phase: Phase 1/Phase 2
Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate
Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate
Enrollment Status: Active_not_recruiting
Publish Date: April 17, 2024
Intervention Type: Radiation
Study Phase: Phase 2
View 8 Less Clinical Trials

144 Total Publications

Cell Type-Specific Effects of miR-21 Loss Attenuate Tumor Progression in MYC-Driven Prostate Cancer.
Cell Type-Specific Effects of miR-21 Loss Attenuate Tumor Progression in MYC-Driven Prostate Cancer.
Journal: bioRxiv : the preprint server for biology
Published: June 04, 2025
View All 144 Publications
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Areas of Expertise

MediFind evaluates expertise by pulling from factors such as number of articles a doctor has published in medical journals, participation in clinical trials, speaking at industry conferences, prescribing and referral patterns, and strength of connections with other experts in their field.

Learn more about MediFind’s expert tiers

Find Dr. Deweese's expertise for a condition
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    • Distinguished
    • Prostate Cancer
      Dr. Deweese is
      Distinguished
      . Learn about Prostate Cancer.
      See more Prostate Cancer experts
    • Advanced
    • Prostatectomy
      Dr. Deweese is
      Advanced
      . Learn about Prostatectomy.
      See more Prostatectomy experts
    • Experienced
    • Bone Tumor
      Dr. Deweese is
      Experienced
      . Learn about Bone Tumor.
      See more Bone Tumor experts
    • Familial Prostate Cancer
      Dr. Deweese is
      Experienced
      . Learn about Familial Prostate Cancer.
      See more Familial Prostate Cancer experts
    • Orchiectomy
      Dr. Deweese is
      Experienced
      . Learn about Orchiectomy.
      See more Orchiectomy experts
    • Pancreatic Cancer
      Dr. Deweese is
      Experienced
      . Learn about Pancreatic Cancer.
      See more Pancreatic Cancer experts
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