Visual Involvement in Giant Cell Arteritis

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This observational study aims to enhance the description of the different ways Giant Cell Arteritis (GCA) affects vision. The latest technology and knowledge are used to improve how we diagnose and predict patient outcomes. GCA is the most frequent vasculitis, an inflammation of vessels, in older adults. It involves large and medium-sized arteries and causes ischemic alterations such as stroke and blindness, through damage of extracranial arteries. The primary objective is to compare the frequency of the various ocular findings between the main alterations of arteritic and non-arteritic aetiology, such as Arteritic Anterior Ischemic Optic Neuropathy (A-AION) Vs. Non-Arteritic Anterior Ischemic Optic Neuropathy (NA-AION) or Central Retinal Artery Occlusion (CRAO) from GCA Vs. from other causes, through a comprehensive clinical and instrumental evaluation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• For GCA group:

‣ Patients older than 18 years with clinically suspected or confirmed gigantocellular arteritis.

⁃ Newly found visual involvement with suspected or confirmed correlation with vasculitis.

⁃ Ability to express valid consent to study enrolment.

• For control group:

‣ Patients older than 18 years with the ability to express valid consent to study enrolment.

⁃ Newly diagnosed acute visual impairment with GCA phenotypes (e.g. AION, CRAO) but without any correlation with vasculitis aetiology.

Locations
Other Locations
Italy
ASST Fatebenefratelli-Sacco
RECRUITING
Milan
Contact Information
Primary
Enrico Tombetti, Prof.
tombetti.enrico@asst-fbf-sacco.it
3289098793
Time Frame
Start Date: 2024-06-27
Estimated Completion Date: 2030-06
Participants
Target number of participants: 762
Treatments
GCA patients
Patients older than 18 years with clinically suspected or confirmed giant cell arteritis, who experience newly diagnosed visual impairment with suspected or confirmed correlation with vasculitis.
Non arteritis patients
Patients over 18 years of age who experience newly diagnosed acute visual impairment with GCA phenotypes (e.g. AION, CRAO) but without any correlation with vasculitis aetiology.
Sponsors
Leads: ASST Fatebenefratelli Sacco

This content was sourced from clinicaltrials.gov