Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: t
View:
• Ages 18-70
• Fulfills the 1990 and 2011 American College of Rheumatology Criteria for FM
• Fulfills the 2010 ACR-EULAR classification criteria for RA
• Healthy volunteers: No significant pain/fatigue/depression/anxiety.
Locations
United States
Florida
University of Florida
RECRUITING
Gainesville
Contact Information
Primary
Roland Staud, M.D.
staudr@ufl.edu
352-294-8200
Backup
Melyssa M Godfrey, BS
melyssa.m.g@ufl.edu
352-265-8901
Time Frame
Start Date: 2022-03-22
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 150
Treatments
Fibromyalgia
Participants who fulfill the 1990 and 2011 American College of Rheumatology Criteria for FM.
Rheumatoid Arthritis
Participants who fulfill the 2010 American College of Rheumatology (ACR)-European League against rheumatism (EULAR) classification criteria for RA.
Healthy Volunteers
Participants who do not have significant pain/fatigue/anxiety/depression.
Related Therapeutic Areas
Sponsors
Leads: University of Florida