Treatment of Negative Symptoms of Schizophrenia by Repetitive Transcranial Magnetic Stimulation: A Naturalistic Study
The purpose of this study is to assess the effectiveness of rTMS on the negative symptoms of schizophrenia in real conditions. It will also provide a regulatory framework to rTMS treatments under these conditions. 4 types of rTMS protocols are proposed, allowing to adapt to patients and their tolerances.Treatment lasts between 2 and 4 weeks, with a follow-up period of 3 months after treatment to observe relapses.To assess the evolution of negative symptoms between baseline and the end of treatment, investigators use SANS (Scale for the Assessment of Negative Symptoms).
• Patient over 18 years of age
• Patient diagnosed with schizophrenia according to the DSM-V criteria (Diagnostic and Statistical Manual of Mental Disorder V5, 2013)
• Stable drug treatment for at least 4 weeks
• Presence or persistence of negative symptoms in the foreground:
⁃ Negative PANSS score ⩾21, positive PANSS score ⩽24
• Patient (or legal representative) willing to participate in the study and having signed an informed consent
• Patient fluent in the French language
• Affiliation to a social security scheme