Bilateral Prefrontal and Insular TMS for Depression in Schizophrenia
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to provide an effective repetitive transcranial magnetic stimulation (rTMS) treatment for depressive symptoms in patients with schizophrenia. Schizophrenia patients with depressive symptoms will be exposed to rTMS to improve their symptoms.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:
• Male and female ages between ages 18-60 years.
• Ability to give written informed consent (age 18 or above).
• Diagnosed with schizophrenia-spectrum disorder and Evaluation to Sign Consent (ESC) above 10.
• Score of Calgary depression scale for schizophrenia (CDSS) ≥ 3.
Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Alina Siatka
Alina.Siatka@uth.tmc.edu
713-486-2740
Backup
Xiaoming Du, PhD
Xiaoming.Du@uth.tmc.edu
443-882-9717
Time Frame
Start Date: 2024-05-21
Estimated Completion Date: 2030-06-01
Participants
Target number of participants: 120
Treatments
Active_comparator: Active rTMS stimulation
Participants will receive active H-coil delivered rTMS in each treatment visit for up to 20 treatment visits for about 4 weeks. In each visit, there are three rTMS sessions with inter-rTMS-session interval of about 30 minutes.
Sham_comparator: Sham rTMS stimulation
Participants will receive sham H-coil delivered rTMS in each treatment visit for up to 20 treatment visits for about 4 weeks. In each visit, there are three rTMS sessions with inter-rTMS-session interval of about 30 minutes.
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Mental Health (NIMH)
Leads: The University of Texas Health Science Center, Houston